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Title: | Multidrug-Resistant Bacteria Colonization in Patients Admitted to Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia |
Authors: | Shahab, Selvi Nafisa Karuniawati, Anis Syarif, Omar Mukhtar Saharman, Yulia Rosa Sinto, Robert Sudarmono, Pratiwi Pujilestari |
Keywords: | multi-drug resistance bacteria colonization healthcare-associated infections |
Issue Date: | Apr-2024 |
Publisher: | Acta Medica Indosiana |
Citation: | Original Article |
Abstract: | Background: Antibiotic resistance is the main problem in infectious disease management. Multidrugresistant (MDR) bacteria could be carried by admitted patients and become a source of spread in the hospital, causing infections in other patients or the patients themselves. However, the screening of MDR bacteria has not been a standard in developing countries. This study aimed to get the prevalence of MDR bacteria colonization in patients on admission to Dr. Cipto Mangunkusumo Hospital. Methods: Selective liquid media with added antibiotics were used for culturing the MDR bacteria. While admitted to the hospital, subjects were sampled and interviewed to fill out a questionnaire. The screening specimens used for this study were throat, navel, rectal, nasal, and armpit swabs. During hospitalization, hospital-acquired infections (HAIs) were recorded. Results: Of 100 patients included in the study, the prevalence of MDR bacteria colonization on admission was 63% (n=63) with the prevalence of CR-GNB, ESBL-PE, and MRSA were 11%, 54%, and 11%, respectively. Two-thirds of the patients with HAIs (n=8/12) were colonized with MDR bacteria. Factors associated with MDR bacteria colonization were the recent use of invasive medical devices and comorbidity, while a factor associated with CR-GNB colonization was the recent use of antibiotics. Conclusion: The prevalence of MDR bacteria colonization in patients on admission to Dr. Cipto Mangunkusumo Hospital in 2022 was 63% (n=63), of which 12.68% (n=8) experienced HAIs during hospitalization. MDR bacteria colonization was associated with the recent use of invasive medical devices and comorbidity. History of antibiotic use was associated with CR-GNB colonization. |
URI: | http://localhost:8080/xmlui/handle/123456789/8934 |
Appears in Collections: | VOL 56 NO 2 2024 |
Files in This Item:
File | Description | Size | Format | |
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191-198.pdf | 888.11 kB | Adobe PDF | View/Open |
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