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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Anugraheni | - |
dc.contributor.author | Rini, Chylen Setiyo | - |
dc.date.accessioned | 2024-11-13T08:07:09Z | - |
dc.date.available | 2024-11-13T08:07:09Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 2088 4559 | - |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/7948 | - |
dc.description.abstract | Papaya (Carica papaya) is found throughout Indonesia. Papaya flowers contain saponin, tannin, alkaloid, and flavonoid compounds which functions as antibacterial. Escherichia coli is a Gram-negative rod bacteria that could be found in the human large intestine as a cause of diarrhea. The study aimed to determine the effect of papaya flower extract and a combination of papaya flower extract with tetracycline antibiotics using the smallest concentration capable of inhibiting 50% of bacterial growth against Escherichia coli bacteria ATCC 25922 using the time-kill test method. This study used the method of Minimum Inhibitory Concentration (MIC) and time-kill. The MIC of the ethanol extract of papaya flower was 2 mg/mL. The time-kill test showed that the death phase was occurred at 4 - 24 hours. The bacteriostatic effect of the extract was obtained at 0 hours to 24 hours, while the antibiotic and its combination with the extracts had a bactericidal effect at 8 hours and 24 hours. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Pharmaciana | en_US |
dc.subject | Papaya flowers (Carica papaya) | en_US |
dc.subject | Escherichia coli | en_US |
dc.subject | MIC | en_US |
dc.subject | Time-kill test | en_US |
dc.title | Effect of papaya flower ethanolic extract (Carica papaya) on the time kill of tetracyclin against Escherichia coli | en_US |
dc.type | Article | en_US |
Appears in Collections: | VOL 13 NO 2 2023 |
Files in This Item:
File | Description | Size | Format | |
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246+–+256.pdf | 515.97 kB | Adobe PDF | View/Open |
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