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Title: | AdaptationoftheGutMicrobiotatoModern DietarySugarsandSweeteners |
Other Titles: | Advances in Nutrition |
Authors: | Rienzi, Sara C Di Britton, Robert A |
Keywords: | dietarysugars artificialsweeteners gutmicrobiome evolution adaptation |
Issue Date: | 2020 |
Publisher: | American Society for Nutrition |
Abstract: | The consumption of sugar has become central to the Western diet. Cost and health concerns associated with sucrose spurred the development and consumption of other sugars and sweeteners, with the average American consuming 10 times more sugar than 100 y ago. In this review, we discuss how gut microbes are affected by changes in the consumption of sugars and other sweeteners through transcriptional, abundance, and geneticadaptations.Weproposethattheseadaptationsresultinmicrobestakingondifferentmetabolic,ecological,andgeneticprofilesalongthe intestinaltract.Wesuggestnovelapproachestoassesstheconsequencesofthesechangesonhost–microbeinteractionstodeterminethesafety ofnovelsugarsandsweeteners. |
URI: | http://localhost:8080/xmlui/handle/123456789/4913 |
Appears in Collections: | VOL 11 NO 3 (2020) |
Files in This Item:
File | Description | Size | Format | |
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616-629.pdf | 1.64 MB | Adobe PDF | View/Open |
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