Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/4900
Title: Coronavirus Disease 2019 (COVID-19) and Nutritional Status: The Missing Link?
Authors: Silverio, Renata
Gonçalves, Daniela Caetano
Andrade, Márcia Fábia
Seelaender, Marilia
Keywords: COVID-19
SARS-CoV-2
BMI
obesity
undernutrition
sarcopenia
immune system
Issue Date: 2021
Publisher: Advances in Nutrition
Series/Report no.: Review;682-692
Abstract: Coronavirus disease 2019 (COVID-19) is an emerging disease that has reached pandemic status by rapidly spreading worldwide. Elderly individuals and patients with comorbidities such as obesity, diabetes, and hypertension show a higher risk of hospitalization, severe disease, and mortality by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. These patients frequently show exacerbated secretion of proinflammatory cytokines associated with an overreaction of the immune system, the so-called cytokine storm. Host nutritional status plays a pivotal role in the outcome of a variety of different infectious diseases. It is known that the immune system is highly affected by malnutrition, leading to decreased immune responses with consequent augmented risk of infection and disease severity. Body composition, especially low lean mass and high adiposity, has consistently been linked to worsened prognosis in many different diseases. In this review, evidence concerning the impact of nutritional status on viral infection outcomes is discussed.
URI: http://localhost:8080/xmlui/handle/123456789/4900
Appears in Collections:VOL 12 NO 3 (2021)

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