Uterine cervical carcinosarcoma; very rare and aggressive behavior; literature review

Abstract

Uterine cervical carcinosarcoma; very rare and aggressive behavior; literature review Özer Birge1, *, Mehmet Sait Bakır1 , Ceyda Karadag1 , Can Dinc1 , Tayup Simsek1 1 Akdeniz University, Department of Gynecology Obstetrics, Division of Gynecologic Oncology, 07010 Antalya, Turkey *Correspondence: ozbirge@gmail.com (Özer Birge) DOI:10.31083/j.ceog.2021.02.2219 This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/). Submitted: 12 July 2020 Revised: 29 September 2020 Accepted: 15 October 2020 Published: 15 April 2021 Background: Carcinosarcomaisararemalignancyofthefemalereproductive system, consisting of carcinomatous and sarcomatous components. It originates from the paramesonephric and mesonephric duct residues and is also called malignant mixed Mullerian tumor. Case Presentation: A 58-year-old post-menopausal woman, gravida 2, parity 2, who had no known diseases and no previous surgery presented to another clinic with pelvic pain that had been persisting for about a year and vaginal bleeding for the past month. There was continuous bleeding that was not associated with coitus, and cervical biopsy was reported as carcinosarcoma of heterologous type (the epithelial part was serous carcinoma and the mesenchymal part was chondrosarcoma); the patient was referred to our clinic and underwent evaluation. Conclusion: EȞfective follow-up is very important considering the aggressive clinical picture of carcinosarcoma cases. It should be kept in mind that metastasis may occur, especially in cases with hypercalcemia and deterioration of the general condition. Keywords Carcinosarcoma; Uterine cervix; Paramesonephric; Mesonephric; Hypercalcemia