A sbiT-sbiRS-gloIo regulatory circuit is involved in oxidative stress tolerance of Stenotrophomonas maltophilia

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Title:	A sbiT-sbiRS-gloIo regulatory circuit is involved in oxidative stress tolerance of Stenotrophomonas maltophilia
Authors:	Wu, Cheng-Mu Lee, Yi-Tzu Lu, Hsu-Feng
Keywords:	Stenotrophomonas maltophilia Glyoxalase I Two-component regulatory system Oxidative stress response
Issue Date:	Oct-2024
Publisher:	Journal of Microbiology, Immunology and Infection
Series/Report no.:	Short Communication;827-831
Abstract:	The sbiT-sbiR-sbiS operon of Stenotrophomonas maltophilia encodes an innermembrane protein SbiT and a SbiS-SbiR two-component regulatory system. A sbiT mutant displayed a growth defect in LB agar. Mechanism studies revealed that sbiT deletion resulted in SbiSR activation and gloIo upregulation, which increased intracellular ROS level and caused growth defect.
URI:	http://localhost:8080/xmlui/handle/123456789/9554
ISSN:	1684-1182
Appears in Collections:	Vol. 57 No. 5 (2024)

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