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dc.contributor.author-Chieh Chen, Cheng-
dc.contributor.authorHsiao, Ke-Yu-
dc.contributor.authorHuey Bai, Chyi--
dc.contributor.authorWang, Yuan-Hung-
dc.date.accessioned2024-12-20T03:06:20Z-
dc.date.available2024-12-20T03:06:20Z-
dc.date.issued2022-12-01-
dc.identifier.issn1684-1182-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/9420-
dc.description.abstractAbstract Background: The COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rapid identification and isolation of patients with COVID19 are critical strategies to contain COVID-19. The saliva antigen test has the advantages of noninvasiveness and decreased transmission risk to health-care professionals. This metaanalysis investigated the diagnostic accuracy of the saliva antigen test for SARS-CoV-2. Methods: We searched for relevant studies in PubMed, Embase, Cochrane Library, and Biomed Central. Studies evaluating the diagnostic accuracy of saliva antigen tests for SARS-CoV-2 were included. The data of the included studies were used to construct a 2 2 table on a per patient basis. The overall sensitivity and specificity of saliva antigen tests were determined using a bivariate random-effects model. Results: Nine studies enrolling 9842 patients were included. The meta-analysis generated a pooled sensitivity of 65.3% and a pooled specificity of 99.7%. A subgroup analysis of the studies performing the chemiluminescent enzyme immunoassay (CLEIA) for participants from airports and public health centers revealed a pooled sensitivity of 93.6%.en_US
dc.language.isoenen_US
dc.publisherElsevier Taiwan LLCen_US
dc.subjectAntigen testen_US
dc.subject; COVID-19en_US
dc.subject; Meta-Analysis;en_US
dc.subjectSaliva;en_US
dc.subjectSARS-CoV-2en_US
dc.titleInvestigation of the diagnostic performance of the SARS-CoV-2 saliva antigen test: A meta-analysisen_US
dc.typeArticleen_US
Appears in Collections:VOL 55 NO 6 Part 1 2022

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