Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/9271
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dc.contributor.authorIrawan, Candra-
dc.contributor.authorElya, Berna-
dc.contributor.authorHanafi, Muhammad-
dc.contributor.authorChany Saputri, Fadlina-
dc.date.accessioned2024-12-19T02:36:05Z-
dc.date.available2024-12-19T02:36:05Z-
dc.date.issued2021-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/9271-
dc.description.abstractAims: This study aims to obtain a stem bark extract of Rhinachantus nasutus (L.) Kurz through the application of ultrasound-assisted extraction (UAE) and reveal: the total phenolic content in the extract; The extract's potential as an antioxidant with copper-reducing strength parameters, and its potential as an antidiabetic by inhibiting alpha-glucosidase activity. Results: The crude ethanol extract of R. nasutus stem bark obtained from the UAE process was 7.4896 g with a yield of 4.99%. The high total phenolic content, namely 677.3343±0.0007 mg GAE / g sample, the antioxidant activity test using the CUPRAC method gave an IC50 value of 18.43±0.20 mg / L. In addition, the ethanol extract of stem bark has a high ability to inhibit the activity of the alpha-glucosidase enzyme with an IC50 value of 10.95±0.28 mg / L. Conclusion: The ethanol extract of the stem bark of R. nasutus from UAE has the potential as a source of antioxidants and antidiabetic. Key words: Alpha-glucosidase enzyme, Antidiabetic, Antioxidant, Rhinachantus nasutus (L.) Kurz, Total phenolics content, Ultrasound-assisted extraction.en_US
dc.subjectAlpha-glucosidase enzyme, Antidiabetic, Antioxidant, Rhinachantus nasutus (L.) Kurz, Total phenolics content, Ultrasound-assisted extractionen_US
dc.titleApplication of Ultrasound-Assisted Extraction on the Stem Bark of Rhinachantus Nasutus (L.) Kurz, Total Phenolic, and Its Potential as Antioxidant and Inhibitor of Alpha-Glucosidase Enzyme Activityen_US
dc.typeArticleen_US
Appears in Collections:VOL 13 NO 5 2021

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