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dc.contributor.authorShen, Bing-Jie-
dc.contributor.authorCheng Lo, Wei--
dc.contributor.author-Ho Lin, Hsien-
dc.date.accessioned2024-12-17T07:35:46Z-
dc.date.available2024-12-17T07:35:46Z-
dc.date.issued2022-04-01-
dc.identifier.issn1684-1182-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/9185-
dc.description.abstractAbstract Background: Cancer is an independent risk factor for tuberculosis (TB). The global burden of incident TB attributable to cancer has never been explored. We aimed to evaluate the cancer-attributable burden of TB. Methods: We estimated the population attributable fraction (PAF) by Levin’s formula. The cancer prevalence rates were derived from the Institute for Health Metrics and Evaluation. The relative risk of TB in cancer patients was estimated by using the National Health Insurance Research Database in Taiwan. The global burden of incidence TB attributable to cancer was the weighted sum of PAFs multiplied by the incidence of TB retrieved from the World Health Organization. Results: Worldwide, the total of incident TB cases attributable to cancer was 115,478 cases with a 95% confidence interval (CI), 110,482e123,007, in 2019. The global PAF of TB due to cancer was 1.85% (95% CI, 1.77e1.97%). The three countries with the highest PAFs were Greenland (7.77%), Canada (7.75%), and the United States of America (6.79%), while the three countries with the highest attributable TB cases due to cancer were China (25,240), India (21,629), and Indonesia (13,917). Cancer of respiratory system contributed to 60,257 of TB cases.Conclusions: This study comprehensively explored the impact of cancer on the global burden of TB. Efforts to reduce cancer risk, delay the occurrence of cancer, or treat latent TB infection in the cancer population could potentially reduce the burden of TB and rely on formulating integrated strategiesen_US
dc.language.isoenen_US
dc.publisherElsevier Taiwan LLCen_US
dc.subjectCancer;en_US
dc.subjectGlobal burden of disease;en_US
dc.subjectPopulation attributable fraction;en_US
dc.subjectTuberculosisen_US
dc.titleGlobal burden of tuberculosis attributable to cancer in 2019: Global, regional, and national estimatesen_US
dc.typeArticleen_US
Appears in Collections:VOL 55 NO 2 2022

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