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dc.contributor.authorKhandibharad, Shweta-
dc.contributor.authorNimsarkar, Prajakta-
dc.contributor.authorSingh, Shailza-
dc.date.accessioned2024-12-17T03:17:11Z-
dc.date.available2024-12-17T03:17:11Z-
dc.date.issued2022-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/9156-
dc.description.abstractCytokines are influential molecules which can direct cells behavior. In this review, cytokines are referred as messengers, immune cells which respond to cytokine stimulus are referred as receivers and the immune cells which gets modulated due to their plasticity induced by infectious pathogen leishmania, are referred as followers. The advantage of plasticity of cells is taken by the parasite to switch them from parasite eliminating form to parasite survival favoring form through a process called as reciprocity which is undergone by cytokines, wherein pro-inflammatory to anti-inflammatory switch occur rendering immune cell population to switch their phenotype. Detailed study of this switch can help in identification of important targets which can help in restoring the phenotype to parasite eliminating form and this can be done through synthetic circuit, finding its wider applicability in therapeutien_US
dc.subjectCytokines Messengers Receivers Reciprocity Followers Synthetic circuiten_US
dc.titleMechanobiology of immune cells: Messengers, receivers and followers in leishmaniasis aiding synthetic devicesen_US
dc.typeArticleen_US
Appears in Collections:VOL 3 2022

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