Please use this identifier to cite or link to this item:
http://localhost:8080/xmlui/handle/123456789/9037
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chen, Chieh-Lung | - |
dc.contributor.author | Teng, Chi-Kang | - |
dc.contributor.author | Chen, Wei-Cheng | - |
dc.date.accessioned | 2024-12-14T06:33:39Z | - |
dc.date.available | 2024-12-14T06:33:39Z | - |
dc.date.issued | 2024-04 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/9037 | - |
dc.description.abstract | Background: There is a lack of information regarding outcomes of elderly patients hospitalized with COVID-19 following the widespread use of COVID-19 vaccines and antiviral agents. Methods: A retrospective study was conducted between January and August 2022, enrolling patients aged 65 years or older. Patients were categorized into two groups: ‘old’ (65e79 years) and ‘oldest-old’ (80 years or more). Multivariate regression was employed to identify independent prognostic factors for in-hospital mortality. Results: A total of 797 patients were enrolled, including 428 old and 369 oldest-old patients. In each subgroup, 66.6 % and 59.6 % of patients received at least one dose of the COVID-19 vaccine, respectively. Approximately 40 % of the patients received oral antiviral agents either before or upon hospital admission. A greater percentage of the oldest-old patients received remdesivir (53.4 % versus 39.7 %, p < 0.001), dexamethasone (49.3 % versus 36.7 %, p < 0.001), and tocilizumab (10.0 % versus 6.8 %, p < 0.001) than old patients. The mortality rate was comparable between the two age subgroups (14 % versus 15.2 %). Independent predictors of in-hospital mortality included disease severity and comorbidities such as end-stage renal disease (ESRD), cirrhosis, solid tumours, and haematologic malignancies. Ageing was not correlated with increased in-hospital mortality across all comorbidity subgroups. Conclusions: In the later stages of the pandemic, with widespread vaccination and advancements in COVID-19 treatments, outcomes for hospitalized elderly and oldest-old patients with COVID-19 have improved. The influence of age on in-hospital mortality has diminished, while comorbidities such as ESRD, cirrhosis, solid tumours, and hematologic malignancies have been associated with mortality. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Journal of Microbiology, Immunology and Infection | en_US |
dc.relation.ispartofseries | Original Article;257-268 | - |
dc.subject | Aged | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Hospitalization | en_US |
dc.subject | Elderly | en_US |
dc.subject | Oldest-old | en_US |
dc.subject | Prognosis | en_US |
dc.title | Clinical characteristics and treatment outcomes among the hospitalized elderly patients with COVID-19 during the late pandemic phase in central Taiwan | en_US |
dc.type | Article | en_US |
Appears in Collections: | Vol. 57 No. 2 (2024) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
257-268.pdf | 562 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.