Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/8946
Title: Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength
Authors: Dwimartutie, Noto
Setiati, Siti
Tamin, Tirza Z.
Retno Prijanti, Ani
Harahap, Alida R.
Purnamasari, Dyah
Keywords: Hand grip strength,
older adults,
pre-frail,
vitamin D level.
Issue Date: 2-Apr-2023
Publisher: Perhimpunan Dokter Spesialis Penyakit dalam Indonesia
Abstract: ABSTRACT Background: Vitamin D deficiency is frequent in older adults and associated with poor musculoskeletal function. The prevalence of pre-frailty is also high in older persons, who may proceed to a frail state. This study aimed to determine the vitamin D levels in pre-frail older adults and its correlation with hand grip strength. Methods: A cross-sectional study was conducted on older adults (age > 60 years) with a pre-frail condition who were visiting the outpatient geriatric clinic at Cipto Mangunkusumo Hospital in Jakarta, Indonesia. Serum levels of vitamin D, measured as 25(OH)D, were determined by enzyme-linked immunosorbent assay (ELISA), and hand grip strength was measured using a Jamar hydraulic dynamometer. Correlations between vitamin D levels and hand grip strength were evaluated by Spearman’s rank correlation coefficient. Multiple linear regression analysis was carried out to assess contribution of variables that influence hand grip strength. Results: Of 95 pre-frail older adults (mean age 70.08 ± 5.35 years), 67.4% were female, and the median vitamin D level was 17.91 (interquartile range/IQR 13.68–26.36) ng/mL. Overall, 11.6% of the participants had normal vitamin D levels, whereas 34.7% and 53.7% had insufficient and deficient levels, respectively. Females were more likely to have inadequacy of vitamin D than males. Those with vitamin D deficiency tended to have a higher body mass index (BMI) and lower vitamin D intake than normal levels. A significant correlation between serum vitamin D levels and hand grip strength was observed (r = 0.283; P = 0.006). After adjusting for age, comorbidities, nutritional status, functional status, BMI, protein intake, and sun exposure score, regression analysis between hand grip strength and vitamin D levels gave standard coefficient beta = 0.255 (P = 0.013). Conclusion: In this study, pre-frail older adults had a high proportion of deficient and insufficient vitamin D levels, and a significant correlation was found between serum vitamin D levels and hand grip strength. Keywords: Hand grip strength, older adults, pre-frail, vitamin D level.
URI: http://localhost:8080/xmlui/handle/123456789/8946
ISSN: 2338-2732
Appears in Collections:VOL 55 NO 2 2023

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