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dc.contributor.authorRizki, Kiki Akhmad-
dc.contributor.authorAzhar, Raden Yohana-
dc.contributor.authorDewayani, Birgitta M.-
dc.contributor.authorFahman, Aulia Novariza-
dc.date.accessioned2024-12-09T02:34:00Z-
dc.date.available2024-12-09T02:34:00Z-
dc.date.issued2024-06-
dc.identifier.citationResearch Articleen_US
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/8800-
dc.description.abstractResponse to chemotherapy for breast cancer can be assessed using the CA 15-3 tumor marker, or through histopathological means such as Miller Payne assessment. This study aimed to explore the correlation between CA 15-3 level and histopathological response in locally advanced breast cancer. This is a cross-sectional study measuring CA 15-3 before and after neoadjuvant chemotherapy using the FAC regiment. This study took place in Dr. Hasan Sadikin Hospital Bandung, Indonesia, from January to August 2022. Data on histopathological responses before chemotherapy and after surgery were also collected. Thirty-nine patients were admitted as subjects. Most patients had invasive carcinoma of no special type (79.5%) and luminal B HER 2 molecular subtype (38.5%). A significant decrease in CA 15-3 level after chemotherapy (from 23.54±18.38 ng/mL to 16.30±6.51 ng/mL) was observed. No significant correlation between CA 15-3 level and Miller Payne histopathological responses were found in the subjects.en_US
dc.language.isoen_USen_US
dc.publisherMajalah Kedokteran Bandungen_US
dc.subjectBreast canceren_US
dc.subjectchemotherapyen_US
dc.subjecthistopathologyen_US
dc.titleCorrelation between CA 15-3 and Miller Payne Histopathological Response in Locally Advanced Breast Cancer Undergoing FAC Regiment Neoadjuvant Chemotherapyen_US
dc.typeArticleen_US
Appears in Collections:VOL 56 NO 2 2024

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