Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/8750
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dc.contributor.authorHazae, Bassam A.-
dc.contributor.authorWardhani, Puspa-
dc.contributor.authorAlbadwi, Fatima-
dc.date.accessioned2024-12-02T07:42:59Z-
dc.date.available2024-12-02T07:42:59Z-
dc.date.issued2024-09-
dc.identifier.citationRiview Articleen_US
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/8750-
dc.description.abstractChronic kidney disease (CKD) is a progressively prevalent global health issue. During the initial phases of the condition, CKD is commonly linked to a tendency for excessive blood clotting. While in the end-stage of disease, patients undergoing hemodialysis have a multitude of hemostatic abnormalities. These include prolonged bleeding time, altered platelet count, prolonged PT and aPTT, elevated FDPs and D-dimer, dysregulated vWF activity, and abnormal thrombin generation. These changes result from a combination of uremic toxicity, endothelial dysfunction, inflammatory states, and the effects of the hemodialysis procedure itself. Understanding these mechanisms is crucial for managing and mitigating the bleeding and thrombotic risks in this patient population. This review aims to systematically investigate the effects of hemodialysis on key hemostasis parameters in CKD patientsen_US
dc.language.isoen_USen_US
dc.publisherPharmacognosy Journalen_US
dc.subjectCoagulationen_US
dc.subjectHemostasisen_US
dc.subjectHemodialysisen_US
dc.subjectEnd-stage Kidney Disease (ESKD)en_US
dc.titleAbnormalities in Hemostatic Parameters Related to Hemodialysis in End-stage Kidney Pathology: A Narrative Reviewen_US
dc.typeArticleen_US
Appears in Collections:VOL 16 NO 5 2024

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