Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7944
Title: Comparison of small molecules VEGFR inhibitors in the treatment of renal cell carcinoma
Authors: Tan, Jie Yi
Jaipuria, Aadya
Priefer, Ronny
Keywords: VEGFR inhibitors
renal cell carcinoma
kidney cancer
progression-free survival
adverse drug events
Issue Date: Jul-2023
Publisher: Pharmaciana
Abstract: Vascular endothelial growth factors receptors (VEGFR) inhibitors play a vital role in the treatment of renal cell carcinoma. These are small molecules that predominantly exhibit anti-angiogenesis activity in conjunction with other anti-tumor effects. These drug therapies are approved for the use in patients as frontline agents or adjuvant therapy in renal cell carcinoma. However, VEGFR inhibitors are associated with undesirable adverse events, with some having a more manageable toxicity profile compared to others. As a result, choice of treatment poses a challenge for healthcare providers and patients. Nonetheless, these agents demonstrate improved disease/progression free survival (DFS/PFS) values and remain a critical component in the treatment of kidney cancer.
URI: http://localhost:8080/xmlui/handle/123456789/7944
ISSN: 2088 4559
Appears in Collections:VOL 13 NO 2 2023

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