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dc.contributor.authorIntan Solikhah, Tridiganita-
dc.contributor.authorPermata Solikhah, Gahastanira-
dc.date.accessioned2024-11-11T07:29:33Z-
dc.date.available2024-11-11T07:29:33Z-
dc.date.issued2021-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/7814-
dc.description.abstractObjective: To evaluate the effect of Muntingia calabura L. leaf extract on the blood glucose level and weight of alloxan-induced diabetic mice. Methods: The mice were injected using 150mg/kg of alloxan intraperitoneally to induce diabetes. Blood glucose level was tested before alloxan injection and 5 days after injection to confirm diabetes development. M. calabura leaf extract with 100 and 300 mg/kg and 600 μg/kg of glibenclamide was given orally for 14 days. Results: The statistical results showed a significant decrease in blood glucose level, especially on day-7 and day-14 in the M. calabura leaf extract treatment group and glibenclamide treatment group compared to the model control group. There was an increase of weight on day-7 and day-14 in the M. calabura leaf extract group and a significant decrease in weight on day-7 in the glibenclamide group compared to the model control group. Conclusion: M. calabura leaf extract had a significant antidiabetic effect that can normalize the weight of alloxan-induced diabetic mice. Key words: Alloxan, Diabetes, Muntingia calabura leaf, Mice.en_US
dc.subjectAlloxanen_US
dc.subjectDiabetesen_US
dc.subjectMuntingia calabura leafen_US
dc.subjectMiceen_US
dc.titleEffect of Muntingia calabura L. Leaf Extract on Blood Glucose Levels and Body Weight of Alloxan-Induced Diabetic Miceen_US
dc.typeArticleen_US
Appears in Collections:VOL 13 NO 6 2021

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