Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7779
Title: Antibacterial activity of mexican sunflower leaf Tithonia diversifolia (Hemsl.) A.Gray Aqueous extract against methicillin-resistant Staphylococcus aureus
Authors: Misrahanum, Misrahanum
Safarah, Zahratul
Ismail, Yulia Sari
Keywords: Antibacterial
aqueous extract of Mexican sunflower leaves
Methicillin-Resistant Staphylococcus aureus
Tithonia diversifolia (Hemsl.) A. Gray
Issue Date: Mar-2022
Publisher: Pharmaciana
Abstract: The research of antibacterial activity of Mexican sunflower leaf Tithonia diversifolia (Hemsl.) A.Gray aqueous extract against Methicillin-Resistant Staphylococcus aureus (MRSA) was carried out. The research aimed to observe the antibacterial activity of Mexican sunflower leaves aqueous extract to inhibit the growth of MRSA with concentrations of 10, 20, 30, 40, and 50%. The extracts were obtained by the maceration method, and the antibacterial activity was tested using the agar well diffusion method. Characterization of Mexican sunflower leaves simplicia were obtained with water level 9%, water-soluble level 21,6%, ethanol-soluble level 10,3%, and total ash level 14,36%. Characterization of Mexican sunflower leaves aqueous extracts were obtained with water level 26,36%, water-soluble level 53,13%, ethanol-soluble level 26,36%, and total ash level 19,98%. Phytochemical screening revealed that aqueous extract of Mexican sunflower leaves contained secondary metabolites of alkaloids, flavonoids, tannins, and saponins. The largest inhibitory zone was shown at a 50% extract concentration with a diameter of 12,40 mm. The aqueous extract of Mexican sunflower leaves was capable to form the inhibition zone on the MRSA growth.
URI: http://localhost:8080/xmlui/handle/123456789/7779
ISSN: 2088 4559
Appears in Collections:VOL 12 NO 1 2022

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