Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7773
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dc.contributor.authorShabrina, Ayu-
dc.contributor.authorSafitri, Erika Indah-
dc.contributor.authorFithria, Risha Fillah-
dc.contributor.authorMunir, Misbahul-
dc.contributor.authorSumantri-
dc.date.accessioned2024-11-11T04:49:57Z-
dc.date.available2024-11-11T04:49:57Z-
dc.date.issued2022-03-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/7773-
dc.description.abstractNutmeg oil contains α-pinene, which can be used as sunscreen. The combination of Tween 80 and PEG 400 can maintain the stability of nutmeg oil microemulsion. This research was a follow-up study that aims to determine the stability of the SPF value and qualitative chemical content of nutmeg seed oil microemulsions (NSM). NSM was made with a nutmeg seed oil concentration of 6.4% and tween 80 and PEG 400 as surfactants and cosurfactants with variations in the ratio of F1 (5: 4), F2 (6: 4), and F3 (7: 4). Nutmeg seed oil and NSM content was analyzed using GC-MS. NSM formula were tested for in vitro SPF value stability by storing NSM in a climatic chamber at 30 °C ± 2 °C with RH 65 % ± 5 % for 4 weeks. The SPF values were calculated every week. GC-MS data were analyzed descriptively and data of SPF value stability were analyzed statistically using one-way ANOVA. The GC-MS results of nutmeg seed oil showed 35 components, including significant compounds, namely αpinene, sabinene, β-phellandrene and also α-terpinolene. GC-MS results of NSM showed those significant compounds were still detected after being formulated in microemulsion. The results of the sunscreen activity test of NSM before storage were 10.31 ± 0.03 (F1); 10.47 ± 0.07 (F2); 10.45 ± 0.03 (F3) and did not show significant change after storage for 4 weeks (p > 0.05). The SPF values of NSM were categorized in maximum activity.en_US
dc.language.isoen_USen_US
dc.publisherPharmacianaen_US
dc.subjectNutmeg Oilen_US
dc.subjectMicroemulsionen_US
dc.subjectSPFen_US
dc.subjectStabilityen_US
dc.subjectGC-MSen_US
dc.titleChemical qualitative analysis and spf value stability of nutmeg seed oil in microemulsions with tween 80 and PEG 400 as surfactants and cosurfactantsen_US
dc.typeArticleen_US
Appears in Collections:VOL 12 NO 1 2022

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