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Title: | Diagnostic performance of 128-slice computed tomography angiography in patients with suspected coronary artery disease |
Authors: | Tran, An Viet Nguyen, Nguyet Minh Ngo, Toan Hoang dkk. |
Keywords: | Coronary artery disease Coronary computed tomography angiography Diagnostic performance Invasive coronary angiography |
Issue Date: | 2023 |
Publisher: | Journal of Taibah University Medical Sciences |
Series/Report no.: | Original Article;1599-1607 |
Abstract: | Objectives: To determine the diagnostic performance and influencing factors of 128-slice coronary computed tomography angiography (CCTA) compared with invasive coronary angiography (ICA) in patients with suspected coronary artery disease (CAD). Methods: A cross-sectional analysis study enrolled 139 patients suspected of having CAD, who underwent and received a 128-slice CCTA and ICA. Results: The patient-based model showed high sensitivity and a positive predictive value of 93.2% and 95.3%, respectively (for stenosis 50%). However, these values were lower when analyzed using vessel-based (85.6% and 81.1%) and segment-based (73.9% and 66.6%) models. Specificity and negative predictive value were highest in the segment-based model, decreasing in vessel- and patient-based models at 96.4% and 95.4%, 90.5% and 90.0%, and 36.4% and 42.1%, respectively (for stenosis 70%). All diagnostic values were reduced when the calcium score was 400 Agatston units. Conclusion: 128-slice CCTA is an optimal, minimally invasive, and high-performance method to diagnose the stenosis and morphology of coronary artery lesions. The diagnostic performance of 128-slice CCTA is very high. Heart rate and body mass index do not affect diagnostic accuracy, whereas a calcium score 400 Agatston units is a factor that causes a decrease in diagnostic performance. |
URI: | http://localhost:8080/xmlui/handle/123456789/7761 |
ISSN: | 1658-3612 |
Appears in Collections: | Vol 18 No 6 (2023) |
Files in This Item:
File | Description | Size | Format | |
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1599-1607.pdf | 2.14 MB | Adobe PDF | View/Open |
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