Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7644
Title: Assessment of baroreflex sensitivity during isometric handgrip exercise and oscillatory lower body negative pressure
Authors: Banodhe, Gagan K.
Badhwar, Smriti
Sharma, Hanjabam B.
Deepak, Kishore K.
Keywords: Baroreflex gain
Baroreflex sensitivity
Isometric handgrip exercise
Maximum voluntary contraction
Oscillatory lower body negative pressure
Issue Date: 2023
Publisher: Journal of Taibah University Medical Sciences
Series/Report no.: Original Article;868-875
Abstract: Objectives: Baroreflex sensitivity (BRS) is an estimate of autonomic control of cardiovascular system via the baroreflex arc. It has been suggested that exercise pressure reflex and muscle metaboreflex override baroreflex during exercise to decrease baroreflex gain, which facilitates the simultaneous rise in blood pressure (BP) and heart rate during the exercise. This study investigated the effects of isometric handgrip exercise (IHE) on baroreflex gain and frequency dependence of baroreflex sensitivity while fluctuations in arterial BP were generated. Methods: Thirteen healthy men performed IHE at 20% and 30% of their maximum voluntary contraction (MVC), while oscillatory lower body negative pressure (OLBNP) of 40 mmHg was applied in 0.1 and 0.25 Hz frequencies. Results: Compared to the OLBNP at 0.25 Hz frequency alone, the baroreflex gain for diastolic BP (DBP) was significantly reduced with the addition of IHE at 20% and 30% of MVC in the high frequency band. At rest (without IHE and OLBNP) the baroreflex gain was significantly more in the high frequency band for DBP, but the baroreflex gain for DBP was not significantly different when IHE þ OLBNP were applied at 20% and 30% of MVC in both frequencies. Conclusions: The significant reduction of DBP baroreflex gain with the addition of graded IHE might indicate that exercise pressure reflex and muscle metaboreflex override baroreflex during exercise to decrease baroreflex gain at a high frequency band (0.25 Hz). The frequency-dependent phenomenon of BRS was altered when IHE and OLBNP were applied, meaning that the frequency dependence of BRS was nullified during IHE.
URI: http://localhost:8080/xmlui/handle/123456789/7644
ISSN: 1658-3612
Appears in Collections:Vol 18 No 4 (2023)

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