Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7606
Title: Effect of Suruhan Leaves (Peperomia pellucida L. Kunth) Extract on Triglyceride Blood Level in Diabetic Rats
Authors: Dinda Maryana, Hafita
Nainggolan, Hotlina
Rusyda Hanifa, Nadia
Keywords: diabetes mellitus,
suruhan plants (Peperomia pellucida [L.] Kunth),
triglyceride
Issue Date: 4-Apr-2024
Publisher: Faculty of Pharmacy Univesrsitas Airlangga
Abstract: Abstract Background: Diabetes Mellitus causes complications, such as hypertriglyceridemia. Indonesia has biological wealth diversity that can be exploited in alternative medicine. One of which is Suruhan plants. Flavonoid contents in the plant extract can normalize blood triglyceride levels. Objective: This study aims to determine the effect of the Suruhan extract (Peperomia pellucida L. Kunth) on blood triglyceride levels in alloxan-induced diabetic white rats. Methods: The induction process used alloxan at a dose of 150mg/kgbw intraperitoneally to 12 rats. The rats were divided into 5 research groups, namely normal rats, diabetic rats, and diabetic rats were given various doses of extract. The treatment was carried out for 14 days. Blood samples for triglyceride examination were taken at the end of the study. Results: blood triglyceride levels were obtained in the normal group (127.67 mg/dl); and diabetic control group (395.67mg/dl); the dose group was 20mg/kg BW (216mg/dl); the dose group was 40 mg/kg BW (159.33 mg/dl) and the dose group was 80 mg/kg BW (143.33 mg/dl) in the statistical test with one way ANOVA (p <0.05) obtained significance with a value of p = 0.000. Conclusions: There is an influence of plant extracts (Peperomia pellucida [L.] Kunth) administration on the blood reduction of triglyceride levels in diabetic white rats induced by alloxan. Keywords: diabetes mellitus, suruhan plants (Peperomia pellucida [L.] Kunth), triglyceride
URI: http://localhost:8080/xmlui/handle/123456789/7606
ISSN: 25808303
Appears in Collections:VOL 11 NO 1 2024

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