Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7518
Title: Inotropes in Chronic Beta-Blocker Therapy
Authors: Alsagaff, Mochamad Yusuf
Susanti, Melly
Thaha, Mochammad
Jonatan, Christian
Keywords: Inotropes
Beta-blocker
Decompensated heart failure
Severe sepsis
Issue Date: May-2021
Publisher: Pharmacogn J.
Citation: Riview Article
Abstract: The increasing rate of cardiovascular disorders contributes to rising hospitalized patients receive chronic oral beta-blocker therapy. Beta-blockers remain one of the fundamental therapy for chronic heart failure. Still, their role in decompensated heart failure and severe sepsis during hospitalization is often debated and inconsistent in clinical practice. In recent years, evidence of the efficacy and clinical outcomes of beta-blockers in acute heart failure (AHF) have accumulated. Clinical research indicates that chronic beta-blockade withdrawals should be prevented, or as soon as hemodynamic stabilization and euvolemic condition are reached, it should be reinstituted. As a subset of AHF patients with low cardiac output required inotropes, the choice of proper agent is fundamental. Different inotropic agents such as inhibitors of the phosphodiesterase, levosimendan, and dobutamine also their associations with beta-blockers are discussed.
URI: http://localhost:8080/xmlui/handle/123456789/7518
Appears in Collections:VOL 13 NO 3 2021

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