Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/7381
Title: Comparison of Clinical Outcomes between Acetylcysteine and Ambroxol in Post Acute Exacerbation of COPD Patients
Authors: Molidia, Sri Rahmat
Pramantara, Dewa Putu
Ikawati, Zullies
Keywords: acetylcysteine
ambroxol
AECOPD
cat score
cough score
Issue Date: Apr-2024
Publisher: Jurnal Sains Farmasi & Klinis
Citation: Original Article
Abstract: acerbation chronic obstructive pulmonary disease (AECOPD) patients. This study aims to compare the clinical outcomes of acetylcysteine and ambroxol administration in post AECOPD patients. The study was cohort design, prospective, to comparison of clinical outcomes of acetylcysteine and ambroxol with post AECOPD outpatients coming for clinical chekups in August 2023 at Respira Lung Hospital Yogyakarta. Clinical outcomes parameters were observed on day zero and thirty for CAT score and day zero and four for cough score. The patients were categorized into two groups: acetylcysteine group (n=30) and ambroxol group (n=30). There was no significant difference between two groupsto change of CAT score and cough score (p>0.05) post AECOPD. The acetylcysteine group compared to ambroxol, there was a mean decrease in morning cough score -1.10±1.11 vs -0.87±1.12 (p=0.228), night cough score -1.53±1.43 vs -1.13±1.31 (p=0.438), and CAT score -2.43±5.45 vs -2.90±3.41 (p=0.391). Providing additional therapy of acetylcysteine or ambroxol in this study did not significantly reducing cough scores and CAT scores in post AECOPD patients.
URI: http://localhost:8080/xmlui/handle/123456789/7381
Appears in Collections:VOL 11 NO 1 2024

Files in This Item:
File Description SizeFormat 
58-66.pdf578.61 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.