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dc.contributor.authorKumboyono, Kumboyono-
dc.contributor.authorChomsy, Indah N.-
dc.contributor.authorFirdaus, Dylan H.-
dc.contributor.authorSetiawan, Meddy-
dc.contributor.authorWihastuti, Titin A.-
dc.date.accessioned2024-11-05T07:49:19Z-
dc.date.available2024-11-05T07:49:19Z-
dc.date.issued2022-
dc.identifier.issn1658-3612-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/7293-
dc.description.abstractObjective: This study aims to determine the protective cardiovascular effect of aerobic exercise training by measuring cluster of differentiation 146 (CD146), circulating endothelial cell (CEC), and high-density lipoprotein- cholesterol (HDL-C) levels in adults. Methods: This study was an experimental pre-post-test without a control group. Forty-five participants were divided into three groups based on aerobic exercise training intensity: low, moderate, and high. Whole blood samples were measured for HDL-C levels. In addition, CEC was isolated from Peripheral Blood Mononuclear Cells (PBMC) samples, then identified by CD146 marker using flow cytometry. Results: CEC percentage and HDL-C increase after aerobic exercise training. There was a significant difference in CEC percentage between the intensity groups. However, there was no difference in HDL-C levels. Conclusion: Aerobic exercise training can protect cardiovascular health by stimulating CEC mobilization, identified by CD146. In addition, an HDL-C level increase also contributes to cardiovascular protection by decreasing inflammation levels, inhibiting low-density lipoproteincholesterol oxidation, improving endothelial regeneration capabilities, and lowering blood glucose.en_US
dc.language.isoen_USen_US
dc.publisherJournal of Taibah University Medical Sciencesen_US
dc.relation.ispartofseriesOriginal Article;701-706-
dc.subjectAerobic exercise trainingen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectCardiovascular protectionen_US
dc.subjectCirculating endothelial cellsen_US
dc.subjectHigh-density lipoprotein-cholesterolen_US
dc.titleProtective cardiovascular benefits of exercise training as measured by circulating endothelial cells and high-density lipoprotein in adultsen_US
dc.typeArticleen_US
Appears in Collections:Vol 17 No 4 (2022)

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