Karakteristik dan Stabilitas Fisik NLC-Koenzim Q10 dalam Sleeping Mask dengan Minyak Nilam

Abstract

Abstract Introduction: patchouli oil has an antioxidant and penetration-enhancing effect. The oil potentially increased the effectiveness of sleeping mask with Coenzyme Q10 (CoQ10) in Nanostructured Lipid Carriers (NLC) as an antiaging cosmetic. Objective: To observed the physical characteristics and stability of NLC-CoQ10 in sleeping masks compared to NLC-CoQ10 in sleeping masks with 1% patchouli oil. Methods: The preparation of NLC-CoQ10 was using the High Shear Homogenization method. NLC-CoQ10 was mix with hydrogel and patchouli oil for F2. While for F1 without patchouli oil. After that, physical characteristics and stability were observed, included organoleptic, pH, and viscosity. Physical stability test observed at room temperature for 90 days. Results: The physical characteristics test showed that F1 had an odor like oleum cacao, while F2 had a specific odor of patchouli oil and a slight odor like oleum cacao. F1 had 6.036 ± 0.011 for pH value, while F2 had 6.062 ± 0.020. There is no significant difference. However, F1 and F2 have different viscosity values. F1 had 199.2 ± 0.7 cp for viscosity value, while F2 had 175.6 ± 7.9 cp. The physical stability test showed that F1 and F2 had pH value scale ranges from 6.055 - 6.336 and viscosity 175.6 - 239.7 cp. The viscosity value of F1 had increased after the 60th day, while F2 on the 90th day. Conclusion: Based on characteristic and physical stability tests can be concluded that F1 and F2 have different odor and viscosity, and F2 is more stable than F1. Keywords: sleeping mask, nanostructured lipid carriers (NLC), coenzyme Q10, patchouli oil