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DC Field | Value | Language |
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dc.contributor.author | Taufik, Irfan Imam | - |
dc.contributor.author | Soewandhi, Sundani Nurono | - |
dc.contributor.author | Nugraha, Yuda Prasetya | - |
dc.date.accessioned | 2024-11-01T03:23:39Z | - |
dc.date.available | 2024-11-01T03:23:39Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.citation | Original Article | en_US |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/7199 | - |
dc.description.abstract | Vitamin C in the cosmetics is known to have many benefits such as a brightening agent, anti-aging and preventing black spots on facial skin. However, vitamin C preparations are easily oxidized and change color in the product, so that a stabilizer is needed to maintain the stability of vitamin C during use and storage. This study aims to determine the effect of hydroxyethyl acrylate/sodium acryloyldimethyl taurate hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer (EMT-10) and sodium metabisulfite on characteristics vitamin C emulgel formulas and determine the optimum emulgel formula through the Design of Experiment (DOE) approach with the Simplex Lattice Design method. Based on study showed that the variable concentrations of (EMT-10) and sodium metabisulfite had a significant effect on viscosity (P<0.05), aroma (hedonic) test (P< 0.05), texture testing (P<0.05), and formula stability (P<0.05). For the variable concentration of EMT-10 and sodium metabisulfite, it did not significantly affect the pH value (P>0.05). The atingoptimum formulation is a composition of 2.305% EMT-10 and 0.194% sodium metabisulfite with a pH response of 4.13, viscosity of 22,547 cps, product color stability with a score of 2, aroma test with a score of 2.29, and texture test with a score of 3.21. The results of testing for pH, viscosity, texture and color stability of the product met the acceptance range, but the aroma needed to be improved to increase the preference score for vitamin C emulgel product | en_US |
dc.language.iso | other | en_US |
dc.publisher | Jurnal Sains Farmasi & Klinis | en_US |
dc.subject | optimization | en_US |
dc.subject | vitamin C | en_US |
dc.subject | design of experiment | en_US |
dc.subject | simplex lattice design | en_US |
dc.subject | copolymer | en_US |
dc.title | Optimasi Formula Emulgel Vitamin C dengan Pendekatan Simplex Lattice Design | en_US |
dc.type | Article | en_US |
Appears in Collections: | VOL 10 NO 1 2023 |
Files in This Item:
File | Description | Size | Format | |
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145-154.pdf | 902.6 kB | Adobe PDF | View/Open |
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