Analisis Faktor Klinik terhadap Kualitas Hidup Pasien Hemodialisis di RSUD dr. Loekmono Hadi Kudus

Abstract

Abstract Background: Chronic kidney disease (CKD) and hemodialysis have a negative impact on HRQoL patients. HRQoL assessment is important to evaluate the quality of healthcare and treatment. Objective: To assess the patient's HRQoL status and determine clinical factors that influence the quality of life of hemodialysis patients at RSUD dr. Loekmono Hadi. Methods: This was a cross sectional study with total sampling techniques in routine hemodialysis patients who meet the inclusion criteria. Sociodemographic and clinical factors used were comorbidities, time on hemodialysis, hemoglobin, urea and creatinine levels obtained from medical records, quality of life was assessed using KDQoL-SF36 consisting of three domains. Description of quality of life based on sociodemographic were analyzed using Independent sample t-tests or Mann-whitney test and one-way ANOVA or Kruskal-walis test. Analysis of clinical factors that affect the quality of life using Spearman correlation coefficient and logistic regression. Results: The average score of quality of life in 60 subjects was 63.20  17.05, while the score for the domain of kidney disease, physical and mental health was 74.52  9.83; 47.41  25.09 and 67.68  20.10. Clinical factors were weakly correlated with the average quality of life score except for time on hemodialysis variable to the physical health domain (r = 0.319). Logistic regression analysis showed that there were no clinical factors that most significantly affected (p > 0.05). Conclusion: The clinical measurements were important information to the physicians regarding therapeutic outcomes, but these parameters weakly correlated with HRQoL. HRQoL assessment was needed as a measure of dialysis adequacy and collaboration of health workers to improve patient HRQoL. Keywords: clinical factor, quality of life, hemodialysis, KDQoL-SF36