Efek Sinergis dari Kombinasi Ekstrak Herba Pegagan (Centella asiatica) dan Ekstrak Daun Kelor (Moringa oleifera) dalam Meningkatkan Fungsi Memori

Abstract

The brain is a nerve center that is very influential on the child's response to see, hear, think, and make movements. Disruption of cognitive function results in stunted development of growth and affects the quality of the growth period of intelligence. The purpose of this study was to determine the best concentration of the combination of Centella asiatica extract and Moringa oleifera extract in improving memory function and learning. The method used is the Radial 8-arm maze test which is used to determine the presence of brain disorders in the form of deficits in learning and memory and using passive avoidance tests to determine memory and cognitive function of the brain. Brain histopathology was examined by counting the number of neuron cells in CA 1, CA 3 and DG. The test results showed that the combination of Centella asiatica extract and Moringa oleifera extract in a 1:1 ratio improved memory and learning functions. Brain histopathology results showed that the combination of extracts was safe to use.