Pengaruh Ekstrak Etanol 90% Daun Kelor Moringa oleifera Lam.) Terhadap Fertilitas Tikus Putih Jantan (Sprague-Dawley)

Abstract

Moringa oleifera Lam. is used as traditional medicine and a source of nutrition. Researches on Moringa oleifera Lam. leaves on fertility have been conducted, but variation results are interesting for further research. This study aimed to determine the effect of the ethanol extract 90% of Moringa oleifera Lam. leaves (EEML) on the fertility using spermatogenesis and aphrodisiac parameters in male white rats (Sprague-Dawley). The male rats were randomly divided into negative group (NaCMC 0.5%) and test groups (50, 200, 800 mg/kg BW). The EEML was administered orally for 15 days. The results of this study indicated that EEML could increase the serum testosterone level. Although not significant (p>0.05), the increase was still in normal concentrations (0.660.54µg/ml). Spermatozoa concentration increased significantly (p<0.05) at a dose of 800mg/kgBW. However, the seminiferous tubule diameter and testicular weight did not significantly increase (p>0.05) at all doses of the test groups. The EEML did not affect the mounting frequency and latency, intromission latency, as well as the frequency of male rats significantly (p>0.05). Based on these results, it can be concluded that EEML has the potential to increase the effect of spermatogenesis compared to the aphrodisiac effect on male rats in 15 days.