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dc.contributor.authorPinaffi-Langley, Ana Clara da C-
dc.contributor.authorDajani, Rosa M-
dc.contributor.authorPrater, M Catherine-
dc.contributor.authordkk.-
dc.date.accessioned2024-09-21T00:59:17Z-
dc.date.available2024-09-21T00:59:17Z-
dc.date.issued2024-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/5946-
dc.description.abstractUnder specific conditions, such as catabolic stress or systemic inflammation, endogenous nutrient production becomes insufficient and exogenous supplementation (for example, through dietary intake) is required. Herein, we propose consideration of a dietary nitrate from plant foods as a conditionally essential nutrient for cardiovascular health based on its role in nitric oxide homeostasis. Nitrate derived from plant foods may function as a conditionally essential nutrient, whereas nitrate obtained from other dietary sources, such as drinking water and cured/processed meats, warrants separate consideration because of the associated health risks. We have surveyed the literature and summarized epidemiological evidence regarding the effect of dietary nitrate on cardiovascular disease and risk factors. Meta-analyses and population-based observational studies have consistently demonstrated an inverse association of dietary nitrate with blood pressure and cardiovascular disease outcomes. Considering the available evidence, we suggest 2 different approaches to providing dietary guidance on nitrate from plant-based dietary sources as a nutrient: the Dietary Reference Intakes developed by the National Academies of Sciences, Engineering, and Medicine, and the dietary guidelines evaluated by the Academy of Nutrition and Dietetics. Ultimately, this proposal underscores the need for food-based dietary guidelines to capture the complex and context-dependent relationships between nutrients, particularly dietary nitrate, and health.en_US
dc.language.isoen_USen_US
dc.publisherAdvances in Nutritionen_US
dc.relation.ispartofseriesPerspective;100158-
dc.subjectnitrateen_US
dc.subjectnitric oxideen_US
dc.subjectnitric oxide synthaseen_US
dc.subjectnitriteen_US
dc.subjectvasodilationen_US
dc.subjectgasotransmitteren_US
dc.titleDietary Nitrate from Plant Foods: A Conditionally Essential Nutrient for Cardiovascular Healthen_US
dc.typeArticleen_US
Appears in Collections:VOL 15 NO 1 (2024)

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