The Association between COVID-19 Vaccine Types and Side Effects Following Vaccination: Cross-Sectional Study

Abstract

The Association between COVID-19 Vaccine Types and Side Effects Following Vaccination: Cross-Sectional Study Alifia Maharani Setyoputri 1 , Chandrayani Simanjorang 1* , Laily Hanifah 1 , Ulya Qoulan Karima 1 1 Public Health Study Program, Universitas Pembangunan Nasional ‘’Veteran’’ Jakarta, Indonesia * Authors Correspondence: chandrayanis@upnvj.ac.id/081375272655 ARTICLE INFO ABSTRACT Many experts agree and believe that the COVID-19 vaccine is the best way to control the COVID-19 pandemic in a sustainable manner. Each type of vaccine has different side effects and effectiveness. Meanwhile, information regarding the relationship between the type of COVID-19 vaccines and side effects in real populations, especially in Indonesia, is still limited. The aim of this study was to investigate the association between COVID-19 postvaccination side effects and COVID-19 vaccine type. From April to

June 2022, a cross-sectional quantitative study will be conducted

in Bekasi City, West Java, Indonesia. The population consists of all

1,885,014 residents of Bekasi City who have received the first dose

of

COVID-19 vaccination. The samples obtained were 428 respondents from online surveys employing a purposive sampling technique. Among 428 participants, there were 50.50% received Inactivated Virus (Sinovac/Sinopharm), 23.80% Viral Vector (AstraZeneca), and 25.70% mRNA (Moderna/Pfizer-BioNTech). The adjusted analysis showed a significant correlation between the type of viral vector vaccine (OR: 26.60; 95% CI: 11.04-64.30) and the type of mRNA vaccine (OR: 1.80; 95% CI: 1.17-3.04) with side effects of COVID-19 vaccination. There was a correlation between the type of vaccines with side effects after controlled variables of sex and history of infection. Article History: Received Feb, 7

th , 2023 Accepted Apr, 10 th , 2023 Published online Jun, 30 th , 2023

Keywords: COVID-19; vaccines; side effects;