Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/5859
Title: Effects of Food-Based Approaches on Vitamin A Status of Women and Children: A Systematic Review
Authors: Nankumbi, Joyce
Grant, Frederick
Sibeko, Lindiwe
Mercado, Evelyn
O’Neil, Kristina
Cordeiro, Lorraine S.
Keywords: vitamin A
women
children
food-based approaches
vitamin A deficiency
Issue Date: Aug-2023
Publisher: Advances in Nutrition
Series/Report no.: Review;1436–1452
Abstract: Vitamin A deficiency (VAD) increases risk for morbidity and mortality. Food-based approaches offer one strategy to improve vitamin A status. This systematic review assessed evidence of the effects of food-based approaches on the vitamin A status of women and children under 5 y. VAD was defined as clinical ocular symptoms, such as loss of vision, and/or retinol plasma or serum concentration <0.70 μmol/L. Searches on food-based approaches to improve vitamin A status were conducted for the period 2011–2022 on PubMed, CINHAL, Web of Science, and Google Scholar using PRISMA guidelines. English-language publications were included. Case studies, unpublished dissertations, and non-peer-reviewed studies were excluded. This review comprises 24 of 27,322 identified studies; 23 included studies focused on provitamin A carotenoids. There were 17,214 participants across the 24 studies with sample sizes ranging from 8 to 3571 individuals. Intervention studies spanned from 3 wk to 2 y. Fifteen (63%) studies were randomized control trials, 7 were cross-sectional, and 2 were longitudinal studies. Most studies (N ¼ 21) used biochemical measurements, for example, serum retinol, to assess vitamin A status; other studies used clinical symptoms (for example, xerophtalmia) or dietary intake. Thirteen (54%) studies reported a statistically significant effect of food-based interventions (N ¼ 8) or an association of diet (N ¼ 5) on vitamin A status. This systematic review indicated that some food-based interventions improved vitamin A status, thus offering a safe and effective delivery mechanism for vitamin A. There appeared to be significant association between vitamin A status and consumption of foods with high concentrations of preformed vitamin A and provitamin A carotenoids. Differences across studies in regard to the period of evaluation, food approaches used, and statistical power may explain the lack of effectiveness of food-based approaches on vitamin A status in some studies.
URI: http://localhost:8080/xmlui/handle/123456789/5859
Appears in Collections:VOL 14 NO 6 (2023)

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