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dc.contributor.authorMilajerdi, Alireza-
dc.contributor.authorEbrahimi-Daryani, Nasser-
dc.contributor.authorDieleman, Levinus A-
dc.contributor.authorLarijani, Bagher-
dc.contributor.authorEsmaillzadeh, Ahmad-
dc.date.accessioned2023-06-14T02:45:37Z-
dc.date.available2023-06-14T02:45:37Z-
dc.date.issued2021-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/4912-
dc.description.abstractNo previous investigation has summarized findings from prospective cohort studies on the association between dietary intake of fiber, fruit, and vegetables and risk of inflammatory bowel disease (IBD). Dietary fiber and its major sources can influence the risk of IBD by modulation of the gut microbiota. This study summarizes findings from published cohort studies on the association between dietary fiber, fruit, and vegetable consumption and risk of IBD. Relevant articles published up to January 2019 were searched via PubMed, MEDLINE, Scopus, Embase, Cochrane Library, and Google Scholar. All prospective cohort studies investigating the association between dietary fiber, fruit, and vegetable intake and risk of IBD were included. Combining 7 effect sizes from 6 studies, no significant association was found between dietary intake of fiber and risk of ulcerative colitis (UC) (RR: 1.09; 95% CI: 0.88, 1.34). However, a significant inverse association was found between dietary fiber intake and risk of Crohn disease (CD) (RR: 0.59; 95% CI: 0.46, 0.74), based on 5 studies with 6 effect sizes. Pooling information from 4 studies, we found a significant protective association between dietary intake of fruit and risk of UC (RR: 0.69; 95% CI: 0.55, 0.86) and CD (RR: 0.47; 95% CI: 0.38, 0.58). We also found a significant inverse association between vegetable consumption and risk of UC (RR: 0.56; 95% CI: 0.48, 0.66) and CD (RR: 0.52; 95% CI: 0.46, 0.59). In conclusion, dietary intake of fruit and vegetables was inversely associated with risk of IBD and its subtypes. Dietary fiber intake was also inversely associated with incidence of IBD and CD, but not with UC. Further studies are warranted to examine the association of other fiber-rich foods with IBD.en_US
dc.language.isoen_USen_US
dc.publisherAdvances in Nutritionen_US
dc.relation.ispartofseriesReview;735-743-
dc.subjectfiberen_US
dc.subjectfruiten_US
dc.subjectinflammatoryen_US
dc.subjectbowel diseaseen_US
dc.subjectintakeen_US
dc.subjectvegetableen_US
dc.titleAssociation of Dietary Fiber, Fruit, and Vegetable Consumption with Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysisen_US
dc.typeArticleen_US
Appears in Collections:VOL 12 NO 3 (2021)

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