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dc.contributor.authorYildiz, Nesibe-
dc.contributor.authorYilmaz, Adnan-
dc.contributor.authorIskender, Hatice-
dc.contributor.authorDokumacioglu, Eda-
dc.date.accessioned2023-06-12T03:33:56Z-
dc.date.available2023-06-12T03:33:56Z-
dc.date.issued2021-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/4814-
dc.description.abstractAssociation Between Cigarette Smoking and Breast Milk Levels of Nesfatin-1, Irisin, and Oxidative Stress Markers Nesibe Yildiz 1 , Adnan Yilmaz 2 , Hatice Iskender 3 , Eda Dokumacioglu 3* 1 Department of Medical Biochemistry, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34096, Turkey 2 Department of Medical Biochemistry, Faculty of Medicine, Recep Tayyip ErdoganUniversity, Rize 53100, Turkey 3 Department of Nutrition and Dietetics, Faculty of Healthy Sciences, Artvin Çoruh University, Artvin 08000, Turkey Abs tra c t Background: Breast milk is a very important functional food in the prevention of metabolic and chronic diseases. This study aimed to investigate the effects of smoking during pregnancy on the concentrations of nesfatin-1, irisin, and oxidative stress markers in breast milk. Methods: This study included two groups of 14 smoking and 14 nonsmoking mothers. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity were measured according to the spectrophotometric method in breast milk samples. Nesfatin and irisin levels were measured by enzyme-linked immunosorbent assay. Results: Levels of nesfatin-1 and MDA of the smoking group were significantly higher than those in the control group (p < 0.001). The SOD activity of the smoking group was significantly lower than that of the control group (p < 0.001). No significant difference was found in the breast milk irisin level between the study groups (p > 0.050). Conclusions: Cigarette smoking increases MDA level and decreases SOD activity in breast milk. Nesfatin-1 levels would increase in accordance with increased oxidative stress, and nesfatin-1 acts as a protective mechanism to limit oxidative damage. K e ywo rds : breast milk, irisin, nesfatin-1, oxidative stress, smokingen_US
dc.subjectbreast milken_US
dc.subjectiris inen_US
dc.subjectnesfatin-1en_US
dc.subjectoxidative stressen_US
dc.subjectsmokingen_US
dc.titleAssociation Between Cigarette Smoking and Breast Milk Levels of Nesfatin-1, Irisin, and Oxidative Stress Markersen_US
dc.typeArticleen_US
Appears in Collections:VOL 25 NO 3 2021

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