Case Report Herlyn-Werner-Wunderlich syndrome with double hematocolpos in one side hemivagina

Abstract

Herlyn-Werner-Wunderlich syndrome with double hematocolpos in one side hemivagina You Jin Kim1,† , Jung Bo Yang1,† , Ye Won Jung1,† , Soo Youn Song1 , Geon Woo Lee1 , Heon Jong Yoo1,* 1Department of Obstetrics & Gynecology, Chungnam National University Hospital, Chungnam National University School of medicine, 282, Munhwa-ro, 301-721 Jung-gu, Deajeon, Republic of Korea *Correspondence: bell4184@gmail.com (Heon Jong Yoo) †These authors contributed equally. Academic Editor: Michael H. Dahan Submitted: 6 February 2021 Revised: 22 February 2021 Accepted: 12 March 2021 Published: 10 June 2022 Abstract Background: Herlyn-Werner-Wunderlich syndrome (HWWS) is an extremely rare Mullerian anomaly consisting of uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis. Although few HWWS cases had been reported in the gynecological literature, most of the reported cases were combined with single hematocolpos. Case: We report here on a case of HWWS with double hematocolpos on one side of a hemivagina combined with ipsilateral renal agenesis. This is the first report of HWWS with double hematocolpos on one side of a hemivagina that was successfully treated with the resection of the vaginal septum. Conclusion: It is important to understand the pathogenesis and clinical features of these anomalies for diagnosis. Keywords: Hematocolpos; Hereditary renal agenesis; Urogenital abnormalities; Herlyn-Werner-Wunderlich syndrome; Mullerian anomaly