Cryotherapy versus Cold Coagulation for Treating Cervical Precancerous Lesions

Abstract

Cryotherapy versus Cold Coagulation for Treating Cervical Precancerous Lesions Krioterapi versus Cold Coagulation untuk Menatalaksana Lesi Prakanker Serviks Abstract Laila Nuranna, Nessyah Fatahan, Alfu Laily Department Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Objective : Elaborating the results and comparison of cryotherapy and cold coagulation for cervical pre-cancer lesion cases in West Cakung Primary Health Center, Jakarta, Indonesia. Methods : Observation was conducted from cervical precancer lesion cases which were found by visual inspection with acetic acid (VIA) method. Those cases were directed into cryotherapy or cold coagulation based on randomization sampling. After 6-months post-therapy, the lesions were assessed. This study was administered on Cakung Barat Health Center, Jakarta, Indonesia, on April-December 2018. Of 10 cases, fi ve were treated using cryotherapy and the rest with cold coagulation. Results : After six months follow up, 1 of 5 patients from each therapy still had VIA positive result. The side effect in form of spotting after 1 month of cryotherapy and cold coagulation were 1/5 and 3/5, respectively. There were no other side effects reported during the 6-months follow up for both treatments. Conclusions : The result of both treatments are relatively the same in converting VIA positive into negative, proved with each therapy have turned 4 for 5 patients with prior VIA positive into negative. The side effects endured by respondents were minimal in 1-month post-therapy, while there were no signifi cant side effects after six months posttherapy. Keywords : cervix, cold coagulation, cryotherapy, precancer lesion. Jakarta Abstrak Tujuan : Memberikan informasi hasil terapi dan perbandingan antara krioterapi dan cold coagulation pada kasus lesi prakanker serviks dan efek samping yang ditimbulkanpada responden di wilayah puskesmas Cakung Barat, Jakarta, Indonesia. Metode : Penelitian bersifat observasi pada beberapa kasus lesi prakanker serviks yang ditemukan dengan pemeriksaan inspeksi visual dengan asam asetat (IVA). Lesi tersebut diterapi dengan krioterapi atau cold coagulation secara acak. Setelah 6 bulan setelah terapi, lesi diperiksa ulang. Penelitian berlangsung di wilayah Puskesmas Kelurahan Cakung Barat, Jakarta, Indonesia pada bulan April – Desember 2018. Total kasus yang dinilai berjumlah 10 kasus dengan pembagian 5 kasus diterapi krioterapi, 5 kasus diterapi cold coagulation. Hasil : Setelah 6 bulan pascapengobatan, 1 dari 5 pasien 1 dari 5 orang yang diterapi krioterapi atau cold coagulation dinyatakan masih IVA positif. Efek samping pengobatan setelah 1 bulan adalah spotting sebesar 1/5 dan 3/5, masing-masing. Tidak ada efek samping yang dikeluhkan pasien setelah 6 bulan paska pengobatan krioterapi dancold coagulation. Kesimpulan : Hasil terapi lesi prakanker serviks dengan krioterapi atau cold coagulation relatifsama, hal ini dibuktikan dengan masing-masing terapi telah mengubah 4 dari 5 pasien dengan IVA positif menjadi IVA negatif. Efek samping minimal dirasakan responden pada 1 bulan pasca pengobatan, sedangkan tidak ada efek samping yang dirasakan setelah 6 bulan pengobatan pascaterapi. Kata kunci : serviks, cold coagulation, krioterapi, lesi prakanker serviks