The Levels of Zinc, Selenium, Iron and Copper in Preterm Pregnancy do not Differ with those of Healthy Pregnancy

Abstract

The Levels of Zinc, Selenium, Iron and Copper in Preterm Pregnancy do not Differ with those of Healthy Pregnancy Kadar Seng, Selenium, Besi dan Tembaga pada Kehamilan Prematur tidak Berbeda dengan Kehamilan Sehat Noroyono Wibowo, Fitriana Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Jakarta Abstract Abstrak Objective : To compare zinc, selenium, iron and copper levels in maternal serum of healthy and preterm pregnancy. Tujuan : Membandingkan kadar seng, selenium, besi dan tembaga pada serum maternal ibu hamil normal dan preterm. Methods :This was a cross-sectional study with preterm and healthy pregnant woman who will carry delivery in Dr. Cipto Mangunkusumo National Hospital and Budi Kemuliaan Hospital Jakarta from January to April 2017. This study was conducted by comparing the levels of each micronutrient in both groups of subjects. Metode : Penelitian dilakukan dengan uji potong-lintang dengan subjek penelitian ibu hamil baik preterm maupun aterm yang akan melaksanakan persalinan di RSUPN Dr. Cipto Mangunkusumo dan RS Budi Kemuliaan Jakarta pada Januari hingga April 2017. Penelitian dilakukan dengan membandingkan kadar masing-masing mikro nutrien pada kedua kelompok subjek. Results : From January to April 2017, there were 53 subjects divided into 30 normal pregnant women and 23 preterm pregnant women. The levels of zinc, selenium iron and copper in preterm pregnancy were 42 μg/dL, 72,39 μg/L, 74 μg/L, and 2144,52 μg/dL. Levels of zinc, selenium, iron and copper in normal pregnancy were 42 μg/dL, 67,27 μg/L, 70,5 μg/L, and 2221 μg/dL. There was no difference in micronutrients level in both groups. Conclusions : This study concluded that there was no difference in zinc, selenium, iron and copper levels in healthy and preterm pregnancy. Hasil : Dalam jangka waktu Januari hingga April 2017 didapatkan 53 subjek penelitian yaitu 30 ibu hamil normal dan 23 ibu dengan kehamilan preterm. Seluruh subjek dimasukkan dalam analisis data. Kadar seng, selenium, besi dan tembaga pada ibu dengan kehamilan preterm secara berurutan adalah 42 μg/dL, 72,39 μg/L, 74 μg/L, dan 2144,52 μg/dL. Sedangkan kadar seng, selenium, besi dan tembaga pada ibu hamil normal secara berurutan adalah 42 μg/dL, 67,27 μg/L, 70,5 μg/L, dan 2221 μg/dL. Tidak ada perbedaan bermakna kadar mikro nutrien pada kedua kelompok subjek. Keywords : copper, iron, pregnancy, selenium, zinc. Kesimpulan : Penelitian ini menyimpulkan bahwa tidak ada perbedaan kadar seng, selenium, besi dan tembaga pada ibu hamil normal dan ibu dengan kehamilan preterm. Kata kunci : kehamilan, seng, selenium, besi, tembaga.