Lipid indices in women blood serum before and after the procedure of removal of mature ovarian teratoma

Abstract

Lipid indices in women blood serum before and after the procedure of removal of mature ovarian teratoma M. Karmowski1*, K. A. Sobiech2*, J. Majda3*, P. Rubisz1*, A. Karmowski1*, L. Hirnle1* 1I Department of Gynecology and Obstetrics, Wroclaw Medical University, Wrocław 2Department of Human Biology, University School of Physical Education in Wrocław, Wrocław 3Department of Laboratory Diagnostics, IV Military Hospital, Wrocław (Poland) Summary Purpose of Investigation: The aim of this study was to find new markers for detection of ovarian neoplasms. Authors decided to compare the lipid indicies in the blood serum of patients undergoing surgery treatment of mature ovarian teratomas. Lack of data on this subject in accessible literature was a stimulating factor for this study. Materials and Methods: The examinations covered two groups of women, each with 32 persons. Fasting blood serum gained from blood samples was analysed, marking before the surgical procedure, on the 7th day, six and 12 months after the procedure. Correlations between lipid indices changes HDL/TCH, HDL/LDL, and ApoA1/ApoB was analysed with use of Spearman correlation test. Results: In all parameters of the lipid metabolism and lipid indices, similar direction of changes - that is a trend direction, has been observed. Conclusions: Lipid indices showed their usefulness in preoperational monitoring, the effectiveness of treatment, and postoperative monitoring of mature ovarian teratomas. Key words: Lipid index; Ovarian neoplasm; Ovarian teratoma; Blood serum; Lipid changes.