Progress in understanding the relationship between long noncoding RNA and endometriosis

Abstract

Progress in understanding the relationship between long noncoding RNA and endometriosis Wenying Yana, Hongmei Hub, Biao Tangb,* a Department of Gynecology, Wangjiang Hospital, Sichuan University, China, No. 24, South Section of First Ring Road, Chengdu City, Sichuan Province, China b Department of Gynecology, Sichuan Maternal and Child Health Hospital, No. 290 Shayan West Second Street, Jinyang Road, Chengdu City, Sichuan Province, China A R T I C L E I N F O Article history: Received 24 February 2019 Received in revised form 5 June 2019 Accepted 10 June 2019 Available online 15 June 2019 Keywords: Endometriosis Non-coding RNA lncRNAs Early diagnosis A B S T R A C T Endometriosis is a common gynecological disease. However, the etiology of endometriosis is still unclear, and current theories cannot fully elaborate its specific pathogenesis. Recently, some research has suggested that the occurrence and development of endometriosis may be related to genetics. Long-chain non-coding RNA (lncRNAs) is a kind of non-protein-coding RNA molecule with a length of 200-100,000 bp. With complex biological functions, lncRNAs play an important role in the normal development of individuals and the progression of various diseases, and lncRNAs have become an important field of medical research in recent years. This paper mainly illustrates the research progress on lncRNAs as they relate to endometriosis. We also provide some ideas for exploring the pathogenesis of endometriosis.