A Comparative Study of Obesity-Related Traits and Serum Lipid Parameters in Cardiovascular Patients from Faisalabad, Pakistan

Abstract

Abstract Background: Obesity and dyslipidemia are significant risk factors for cardiovascular disorders (CVDs), yet have not been extensively studied in Pakistani subjects. Therefore, this retrospective observational study was undertaken to investigate the association of obesity-related traits and serum lipid parameters in CVD patients from Faisalabad, Pakistan. Methods: A total of 403 CVD patients and 226 healthy controls were included. CVD patients were enrolled from the Allied Hospital and the Faisalabad Institute of Cardiology. Obesity-related traits [body mass index (BMI), waist and hip circumference (WC and HC), and waist-to-hip ratio (WHR)], serum lipid parameters, and blood pressure of all subjects were measured. Data was analyzed in SPSS v.21. Results: Results showed significantly higher WC, HC, WHR, systolic and diastolic blood pressure in CVD patients as compared to healthy controls. Likewise, there were significant gender specific differences in these parameters in both the CVD patients and healthy control groups. Additionally, Pearson analysis revealed significant correlations between lipid parameters and obesityrelated traits in CVD patients. Conclusion: This study showed a significant correlation between lipid profile and obesity-related traits in CVD patients from Faisalabad, Pakistan. These findings highlight the importance of early management of dyslipidemia and obesity to prevent later sequelae of CVD. Keywords: body mass index, cardiovascular disease, obesity, Pakistan