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Title: | Sleep Quality Affects Humoral Response in Recipients of Two-Dose Sinovac Vaccines |
Authors: | Hananta, Linawati Larasati, Victoria Surilena |
Keywords: | Antibody, SARSCoV-2, Sleep Quality, COVID-19 Vaccine |
Issue Date: | Apr-2023 |
Publisher: | Jurusan Kesehatan Masyarakat Fakultas Ilmu Keolahragaan (UNNES) |
Abstract: | Abstract To curb the COVID-19 pandemic, the government distributed Sinovac vaccines. Sleep mediates immune function, including post-vaccination antibody response. This study aimed to analyze whether there was a difference in post-vaccination antibody levels in Sinovac vaccine recipients with poor and good sleep quality. This study used analytical observations of recipients of the two-dose Sinovac vaccine in 2021. Primary data included age, sex, the Pittsburgh Sleep Quality Index (PSQI) questionnaire, and post-vaccination IgG-SARS-CoV-2 antibody levels. The PSQI and IgG SARS-CoV-2 antibody levels were measured a month after the second vaccination. Participants with non-reactive antibody levels before the first vaccination were included, and participants with incomplete data were excluded. The Mann-Whitney test was used to find associations between sleep quality and post-vaccination IgG SARS-CoV-2 levels. The univariate analysis showed that of 54 participants, 37 (68.5%) were male, and 28 (51.9%) had poor sleep quality. 15 participants (27.78%) were in the 36-45 age group, and median antibody levels in participants who received the second Sinovac Vaccine was 223.5 (199.01) units/mL. Postvaccination IgG SARS-CoV-2 antibody levels were significantly associated with sleep quality (p=0.036). |
URI: | http://localhost:8080/xmlui/handle/123456789/11151 |
ISSN: | 2355-3596 |
Appears in Collections: | VOL 18 NO 4 2023 |
Files in This Item:
File | Description | Size | Format | |
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6. 41950-117793-2-PB.pdf | 225.83 kB | Adobe PDF | View/Open |
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