Hubungan kadar kolesterol total dengan kejadian peripheral artery disease pada penderita diabetes melitus

Abstract

Abstract Background: One of the countries facing the problem of non-communicable diseases (NCDs) is Indonesia and they are the cause of 63% of deaths, one of which is diabetes mellitus (DM). Every year, the incidence of DM continues to increase, which can cause chronic complications, peripheral artery disease (PAD). PAD is caused by atherosclerosis in the walls of the leg arteries which can be triggered by the presence of excess cholesterol in the body. Purpose: To analyze the relationship between total cholesterol levels and the incidence of PAD in DM sufferers. Method: The research design used a correlational descriptive design with a cross sectional approach to analyze the relationship between total cholesterol levels and the incidence of peripheral artery disease (PAD) in DM sufferers. The population in this study was 106 DM patients who were hospitalized at UNS Hospital in the period January-August 2023. The sampling technique used purposive sampling, so the total sample was 52 patients without diabetic foot ulcers. Results: The relationship between total cholesterol levels and the incidence of PAD in DM sufferers was tested using the Spearman Rank correlation test which showed a strong correlation (r=0.614) and a significant p-value of 0.001. The test decision is that H0 is rejected and Ha is accepted because the p-value is smaller than 0.05 (0.001<0.05). Conclusion: There is a strong relationship between total cholesterol levels and the incidence of PAD in DM sufferers. Suggestion: DM sufferers can control total cholesterol levels within normal limits by avoiding trigger factors such as cigarette smoke, alcohol consumption and foods high in saturated fat. Sufferers are expected to consume foods high in fiber, such as fruit and vegetables and carry out regular physical activity. Keywords: Diabetes Mellitus; Peripheral Artery Disease (PAD); Total Cholesterol.