http://localhost:8080/xmlui/handle/123456789/9121 1135 - 1336 Wed, 08 Apr 2026 15:41:42 GMT 2026-04-08T15:41:42Z http://localhost:8080/xmlui/handle/123456789/9494 Title: Evaluation of the Rapid Sepsityper protocol and specific MBT-Sepsityper module for the identification of bacteremia and fungemia using Bruker Biotyper MALDI-TOF MS Abstract: Abstract The rapid identification method, the Rapid Sepsityper protocol with a specific MBTSepsityper module (Bruker Daltonics), based on the MALDI Biotyper platform, accurately identified 93.5% (116/124) of microorganisms at the species level in the 124 flagged blood culture samples from patients with monomicrobial bloodstream infections. Gram-negative bacilli (95.6%, 43/45) had a higher identification rate than Gram-positive cocci (93.3%, 70/75) and yeasts (75%, 3/4). The Rapid Sepsityper protocol displayed poor identification performance for polymicrobial samples. Thu, 15 Dec 2022 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/9494 2022-12-15T00:00:00Z http://localhost:8080/xmlui/handle/123456789/9493 Title: An outbreak of human Rhinovirus-A21 infection in a psychiatric ward during COVID19 pandemic Authors: -Chiung Chen, Lung; -Chien Chiu, Chih; Chang, Fu-Mei; Yuan Wu, Pei-; Yang, Shu-Li; -Guei Huang, Chung Abstract: Abstract A cluster of acute respiratory illnesses involving 12 inpatients and 3 healthcare workers occurred in a psychiatric ward. Eight of them were identified as HRV-A21. Fever and cough were the most common symptoms. The study also provides further evidence of the impact of HRV on lower respiratory tract illness. Thu, 15 Dec 2022 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/9493 2022-12-15T00:00:00Z http://localhost:8080/xmlui/handle/123456789/9492 Title: Reducing catheter related bloodstream infection risk of infant with a prophylactic antibiotic therapy before removing peripherally inserted central catheter: A retrospective study Authors: -Ru Yan, Pei; Chi, Hsin; Chang Chiu, Nan-; -Ying Huang, Ching; Tsung-Ning Huang, Daniel Abstract: Abstract Purpose: This study examined the efficacy of prescribing antibiotics, specifically a single dose of vancomycin, in reducing the incidence of culture-positive and culture-negative sepsis prior to the removal of peripherally inserted central catheters (PICCs). Materials and methods: We retrospectively reviewed charts of infants who had PICCs in a tertiary level hospital during the period from 2010 to 2019. The incidence of post-catheter removal clinical sepsis between the groups with or without antibiotics was compared. The antibiotic group was defined by receiving a single dose of vancomycin or any other antibiotic prior to line removal. Results: We enrolled 585 PICC removal episodes in 546 infants for analysis. Antibiotics were given prior to removal in 257 cases (43.9%) and not given prior to removal in 328 cases (56.1%). There were 13 episodes of post-catheter removal clinical sepsis detected within 72 h (2.2%), 2 of which were culture-positive (0.3%). A 9.3-fold decrease in the odds for clinical sepsis was observed in the antibiotic group (p Z 0.01). The incidence of post-catheter removalsepsis was decreased by a single prophylactic dose of vancomycin (p Z 0.02), whereas the use of other antibiotics showed no effect (p Z 0.35). Logistic regression analysis demonstrated that comorbidities with gastrointestinal diseases (p Z 0.01), PICC insertion sites in the scalp and neck (p Z 0.04), and no vancomycin administration prior to line removal (p Z 0.02) were independent risk factors for subsequent clinical sepsis. Conclusion: A single prophylactic dose of vancomycin prior to PICC line removal might reduce clinical sepsis events in infants Thu, 15 Dec 2022 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/9492 2022-12-15T00:00:00Z http://localhost:8080/xmlui/handle/123456789/9491 Title: Determinants of latent tuberculosis infection and treatment interruption in longterm care facilities: A retrospective cohort study in Taiwan Authors: Fang Chiu, Ting-; -Yong Yen, Muh; -Huei Shie, Ying; Lan Huang, Hui-; -Chieh Chen, Chu; Feng Yen, Yung- Abstract: Abstract Background/purpose: Latent tuberculosis infection (LTBI) treatment is challenging in long-term care facilities (LTCFs) residents due to the occurrence of medical complexities. However, factors associated with treatment interruption have not been extensively studied. This retrospective cohort study aimed to determine LTBI-associated factors and treatment interruption in LTCF residents and employees in Taiwan. Methods: From May 2017 through September 2020, the residents and employees of 20 LTCFs in Taipei, Taiwan, were screened for LTBI by using QuantiFERON-TB Gold In-Tube test. The LTBI individuals underwent directly observed preventive therapy (DOPT), including regimens of 9- month daily isoniazid (9H) and 3-month weekly isoniazid plus rifapentine (3HP). All the LTBI cases were followed up till treatment completion, death, or treatment interruption. Results: Among 2207 LTCF subjects, 16.8% had LTBI. After controlling for other covariates, residents of public facilities had a significantly higher LTBI prevalence than those of privatefacilities (adjusted odds ratio [AOR] Z 1.43; 95% confidence interval [CI]: 1.08e1.88). Among 264 LTBI cases receiving preventive therapy, 52 (19.7%) had treatment interruption. LTBI cases receiving 3HP were less likely to have treatment interruption than those receiving 9H (AOR Z 0.22; 95% CI: 0.07e0.71). Conclusions: LTCF residents, particular those living in public facilities, had a high LTBI prevalence. 3HP with DOPT is considered the priority regimen for preventive therapy among LTBI cases in LTCFs. Thu, 15 Dec 2022 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/9491 2022-12-15T00:00:00Z