http://localhost:8080/xmlui/handle/123456789/6004 Thu, 09 Apr 2026 14:58:55 GMT 2026-04-09T14:58:55Z http://localhost:8080/xmlui/handle/123456789/6060 Title: THE EFFECT OF LOW-FIBER DIETS ON COLORECTAL CANCER INCIDENCE IN SOUTHEAST AND EAST ASIA: SYSTEMATIC REVIEW AND METAANALYSIS Authors: Novianti, Tia Eka; Rachmah, Qonita; Adriani, Merryana Abstract: ABSTRACT Introduction : Colorectal cancer is a malignant tumor that grows in the colon tissue. In the Asian region, in 2018, cases and deaths from colorectal cancer are highest in East Asia (there were 736,573 cases and 325,128 of them died) and Southeast Asia (there were 95,223 cases and 52,475 of them died). Aims: Several studies have been conducted regarding the effect of a low-fiber diet and an increased risk of colorectal cancer, but it still shows mixed results. Methods: This study is an unobstrutive study with a systematic review and meta-analysis method. Data sources came from 14 primary studies with a case-control study design that met the inclusion criteria. Data analysis was performed using CMA software trial version 3.0 with a confidence level of α = 5%. Research with low-fiber diet variables shows heterogeneous variations in results so that the chosen model is random effect model. Result: The analysis states that there was a significant relationship between a low-fiber diet (CI: 0.421–0.867) and an increased risk of colorectal cancer due to the role of soluble and insoluble fiber. Lack of intake of soluble fiber can decrease insulin action and blood sugar control or the production of shortchain fatty acids, whereas insufficient intake of insoluble fiber can increase the potential for interactions between mutagens and colonic mucosa. Conclusion: The results of the study are expected to be an input for a proper diet so that there is no increase in cases of colorectal cancer. Keywords: colorectal cancer, low-fiber diet, meta-analysis, systematic review Tue, 01 Aug 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/6060 2023-08-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6059 Title: LEADERSHIP STYLE INFLUENCE ON NURSES’ BURNOUT: A SYSTEMATIC REVIEW Authors: Syanindita Roshida, Devy; Paskarini, , Indriati; Martiana, Tri Abstract: t literature, published from 2019 to 2022 and study the types of leadership styles and how they affected nurse burnout. Aims: the research was to systematically review the influence of leadership style on nurse burnout. Methods A systematic literature search was conducted through an electronic search in three databases and was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) with some inclusion criteria compiled by the research objective. Results A total of 15 selected articles show that leadership styles affected nurse burnout both directly and indirectly. This systematic review shows that some leadership styles had an influence on increasing nurse burnout, as well as affecting their job satisfaction, psychological distress and their intention to leave. Some other leadership styles also influenced reducing nurse burnout and increasing their work engagement. Conclusions Due to the variety of leadership styles studied in the articles, it’s hard to draw specific conclusions. However, this systematic review shows most of the articles stated that some specific leadership styles took part in increasing nurse burnout, and some other leadership styles were able to reduce nurse burnout in particular. Keywords: Burnout, Leadership style, Nurse Tue, 01 Aug 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/6059 2023-08-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6058 Title: STRENGTHENING IMPLEMENTATION 5S WORK CULTURE TO FINANCIAL PERFORMANCE AND PRODUCTIVITY AT PT PETROKIMIA GRESIK Authors: Frecelia Putri, Windy; Sriyono, Sriyono; Panggah Setiyono, Wisnu Abstract: ABSTRACT Introduction: The preliminary, applying Japanese housekeeping, namely the 5S such as Seiri, Seiton, Seiso, Seiketsu, and Shitsuke, is one way to achieve these five qualities. 5S is a procedure that controls and standardizes the workplace by ensuring the efficiency of business processes to provide a safe and high-quality workplace. Aims: This research was a case study that aimed to observe how the 5S was implemented as a work culture and how it influenced organizational performance. Method The research was qualitative research using an ethnography approach through the description of the data collected through field observation. The data analysis included data reduction, data presentation, and drawing conclusions. It was found by observing indicators that activities that needed development were found, such as: Sort Out = 4, Set in Order = 1, Sweep = 1, Standardize = 2 and Sustain = 1. Results Findings show that the previously unfavorable working conditions of employees have now improved and can be further improved by implementing 5Ss. The results show that if the subsidiary has an increase in financial performance, it can be seen from the overall average value of Assets = 0.00103 and the GPM value = 0.547 is higher than before. Conclusion Increased work efficiency and effectiveness are well-coordinated and work quality and safety are well-maintained. Then the financial performance changed greatly, which initially declined due to the weakness of the 5S work culture, has now drastically improved thanks to the 5S work culture that was successfully strengthened. Keywords: Implementation, 5S, observation Tue, 01 Aug 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/6058 2023-08-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6054 Title: A DESCRIPTIVE COMPARISON OF RESPONSE OF ORAL HYPOGLYCEMIC AGENTS AMONG T2DM IN A BACKDROP OF INSULIN RESISTANCE Authors: Chakraborty, Sandip; Karmakar, Amrita; Dawn, Indranil; Samadder, Sangita; Mandal, Dipa Abstract: ABSTRACT Introduction:Different homeostatic models for the assessment of beta cell function in patients with insulin resistance in type 2 diabetes mellitus suggest that Dipeptidyl Peptidase (DPP-4) inhibitors cause less beta cell stress. Aims: The present study aimed to compare and contrast insulin resistance in two groups of patients taking oral hypoglycemic agents, DPP-4 plus metformin and glimepiride plus metformin, on the basis of fasting and postprandial c-peptide and insulin resistance estimated by homeostatic model assessment of insulin resistance (HOMA-IR). Methods: This preliminary descriptive observational study was conducted from 2018 to 2019 in the service Laboratory of the Department of Biochemistry, in collaboration with the Endocrinology Department, Nil Ratan Sircar Medical College and Hospital, Kolkata. Serum C-peptide, serum insulin, and plasma glucose levels were measured in both fasting and post-prandial states along with glycated hemoglobin. Result: In the fasting and fed state, the secretagogue effect of glimepiride-metformin combination was significantly higher (p = 0.017) than that of the linagliptin-metformin combination. Conclusion: Patients treated with glimepiride showed high post prandial insulin levels and high post prandial glucose excursion. This finding can be explained by the probable increase in insulin resistance, which is reflected in their post-prandial C peptide level. However, in the case of linagliptin, one mechanism of decreased postprandial glucose is believed to be the inhibition of α-cell glucagon release, thereby relieving β-cell stress. Keywords: DPP-4, GLP-1, HOMA-IR, OHA, T2DM Tue, 01 Aug 2023 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/6054 2023-08-01T00:00:00Z