http://localhost:8080/xmlui/handle/123456789/10447 Thu, 09 Apr 2026 04:02:16 GMT 2026-04-09T04:02:16Z http://localhost:8080/xmlui/handle/123456789/10455 Title: Drug-Drug Interactions (DDIs) in Elderly Hypertensive Inpatients of the Academic Hospital of Universitas Gadjah Mada Yogyakarta Authors: Titami, Arina; Wiedyaningsih, Chairun; Putu Pramantara, I Dewa Abstract: Background: The prevalence of hypertension is higher among the elderly population. Elderly patients are considered a high-risk population for Drug-Drug Interactions (DDIs) due to multi-morbidity-related polypharmacy, age-related physiological changes, as well as pharmacodynamic and pharmacokinetic changes. Objectives: This study conducted a drug use survey in the inpatient department of the Academic Hospital of Universitas Gadjah Mada Yogyakarta to assess Drug-drug interactions (DDIs) in individual prescriptions for elderly hypertensive patients. Methods: This research employs an observational study design with a retrospective cohort approach. This study conducted at the Academic Hospital of Universitas Gadjah Mada Yogyakarta in January-December, 2021. The inclusion criteria for this study included patients diagnosed with hypertension, aged 60 years or older and those hospitalized. Results: 120 prescriptions from 120 patients were collected from the medical records maintained by the Academic Hospital of Universitas Gadjah Mada Yogyakarta. This study identified 62 cases of Drug-Drug Interactions (DDIs), mainly due to drug interactions comprising 8 interactions unrelated to hypertension, and 54 related to hypertension. Three actual drug interaction events resulted in increased blood pressure, while the others were potential drug interactions. The most common occurrence of antihypertensive drug interactions in this study was at a moderate level of 54 events (87%). Conclusion: From this study, it can be concluded that elderly patients are considered a natural high-risk population for DDIs. Each patient should be assessed individually based on their prescriptions, although in many cases, DDIs are unavoidable. Keywords: Drug-Drug Interactions; Elderly; Hypertension; Inpatients Wed, 01 Jan 2025 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/10455 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/10454 Title: Factors Affecting Job Satisfaction Among Community-Pharmacists with VIJS Instrument in South Sulawesi Authors: Nur’ainun Reskia Pawallang, Andi; Suryo Prabandari, Yayi; Quang Trung, Vo; Ari Kristina, Susi Abstract: Background: Pharmacists' responsibilities have shifted over time. Pharmacists have grown increasingly clinically involved in patient care from delivering pharmaceuticals throughout the healthcare system. These developments may have influenced pharmacists' job satisfaction. This is significant since performance, motivation, and productivity are all positively associated with job happiness, whereas a lack of job satisfaction may hurt patient care and safety and increase job turnover. Objectives: To analyze the factors affecting job satisfaction among community pharmacists in South Sulawesi. Methods: This research uses quantitative and analytical observational research with a cross-sectional study design. This research was conducted from mid-January to mid-March of 2024, with the research subject being community pharmacists who worked at pharmacies, primary healthcare, and clinics in the South Sulawesi region. Research instruments are distributed to each IAI branch management in South Sulawesi via Google Forms. The instruments used in this research were sociodemography, pharmacist service characteristics, and the job satisfaction questionnaire (VIJS Instrument). The analysis used is univariate analysis (descriptive), bivariate analysis (independent T-test), and multivariate analysis (multiple regression linear analysis). Results: The general result of this research is satisfied based on the mean score (3.8±0.8). The lowest mean score from both factors is monthly income (3.1±1.1) and learning and advancement opportunity (3.3±1.1). The regression analysis indicated that factors affecting job satisfaction among community pharmacists in South Sulawesi are monthly income (p=0.025), long working period (p=0.019), number of patients per day (p=0.008), and number of prescriptions per day (p=0.005). Conclusion: Community pharmacists in South Sulawesi are satisfied with their work, and their satisfaction level is affected by monthly income, long working periods, the number of patients per day, and the number of prescriptions per day. Keywords: Job Satisfaction, Community Pharmacy, South Sulawesi Wed, 01 Jan 2025 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/10454 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/10453 Title: Adaptation of the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) to Indonesian for Chronic Diseases Patients Authors: Viviandhari, Daniek; Wulandari, Nora; Nurhasnah, Nurhasnah Abstract: Background: National data indicate an increase in chronic disease prevalence. Therapeutic outcomes need to be assessed based on the aspects of the patient’s psychology, including treatment satisfaction. In Indonesia, no native or cross-culturally adapted treatment satisfaction tool is available and validated for chronic disease patients. Objectives: The study is intended to conduct cross-cultural translation and adaptation of the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) into Indonesian and to evaluate the questionnaire’s reliability and validity in the Indonesian context. Methods: SATMED-Q translation and adaptation were conducted following a systematic procedure: forward translation, synthesis, backward translation, expert committee review, and pre-testing. The samples were hypertension and type 2 diabetes mellitus patients at the primary health care center. The internal consistency and known-group validity were analyzed statistically. Results: A total of 45 participants were involved in the research to assess the reliability and validity of the translated questionnaire. Some grammatical changes were made on the forward translation, the back translation, and the expert committee review stage. The major changes were the definition of the Likert-type scale on each domain. The reliability test showed good consistency (Cronbach’s alpha=0.842). Certain factors (gender and working status) showed known group validity, but not the number of antihypertensive or antidiabetic medications. Compared to individuals who took two medications, people who took one medicine indicated less satisfaction with their treatment. Conclusion: The translation and cross-cultural adaptation of the SATMED-Q to Indonesian was satisfactory. The Indonesian version of SATMED-Q was a reliable and valid instrument to assess treatment satisfaction. Keywords: Chronic diseases; Cross-cultural adaptation; SATMED-Q; Treatment satisfaction Wed, 01 Jan 2025 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/10453 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/10452 Title: Path Analysis Study on the Direct and Indirect Effect of Factors Affecting Performance of Pharmaceutical Staff in Primary Health Centers in Bandung Authors: Roseno, Mohammad; Widyastiwi, Widyastiwi Abstract: Background: Pharmaceutical staff plays an essential role in pharmaceutical services. Despite their role, several factors have been reported to cause suboptimal provision of pharmaceutical services. Objectives: This study aimed to examine the impact of physical environment, compensation, and motivation on organizational culture, and its implication on performance of pharmaceutical staff. Methods: The sample population comprised 149 pharmaceutical staff from 71 Primary Health Centers in Bandung, selected using total sampling. The inclusion criteria were pharmaceutical staffs in 71 Primary Health Centers in Bandung. Pharmacy personnel who refused to give consent or did not complete filling out instruments were excluded. Data were collected using a questionnaire to assess the participants’ perceptions of physical environment, compensation, motivation, organizational culture, and performance. Direct and indirect effect of each variable and its correlation was determined by path analysis. All analysis were performed by using the SPSS version 25. Results: The physical environment, compensation, motivation, and organizational culture contributes 66.4% to overall performance of pharmaceutical staffs. Physical environment and motivation significantly influenced performance (=0.331 and =0.245, respectively) directly and indirectly through organizational culture. Compensation had neither direct and indirect impact on performance. Organizational culture has a direct effect on pharmaceutical performances (=0.789). Organizational culture is an intervening variable of the physical environment and motivation impact on performance. Conclusion: These findings suggest that the physical environment dan motivation directly influenced performance of pharmaceutical staffs, while financial compensation had no direct or indirect impact. Organizational culture significantly influences the performance by intervening the physical environment and motivation factors. Keywords: Compensation; Motivation; Organizational culture; Performance of pharmaceutical staff; Physical environment Wed, 01 Jan 2025 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/10452 2025-01-01T00:00:00Z