http://localhost:8080/xmlui/handle/123456789/7343 929 - 1098 2026-04-08T23:14:10Z http://localhost:8080/xmlui/handle/123456789/7391 Title: Radicular variant of dens in dente (RDinD) in a patient undergoing radioisotope therapy Authors: Verma, Shiwangi; Dasukil, Saubhik; Sable, Mukund Namdev; Routray, Samapika Abstract: Dense in dente is a developmental anomaly frequently encountered in permanent maxillary incisors, with a prevalence rate of 0.25e10%. Our review of the scientific literature on a radicular variant of dens in dente (RDinD) in permanent molar teeth identified only two reported cases with a confirmed diagnosis. Here, we report the third case of RDinD, in a 37-year-old woman presenting with nocturnal pain in the left maxillary second molar for 1 week. The patient had a medical history of surgery for papillary thyroid carcinoma followed by radioactive iodine therapy. We established a diagnosis of RDinD with an osteolytic lesion and transverse fracture line along the palatal root of the tooth by using cone beam computed tomography (CBCT). Extraction and periapical curettage of the lesion were performed, and the patient was followed up. In summary, we observed a rare clinical presentation of RDinD in the left maxillary second molar of a 37-yearold female patient. 2022-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7390 Title: Prevalence of anemia in pre-school tribal children with reference to parasitic infections and nutritional impact Authors: Panchal, Shital S.; Mishra, Umang; Kothari, Charmy; Kothari, Vijay; Dalai, Sarat; Mecwan, Marcellin; Chaudhary, Shrishma; Sharma, Juhi; Shah, Priyanka Abstract: Objectives: Anemia is a global health problem and has very high prevalence in developing as well as developed countries, particularly in children and women. The present study evaluates hematological predictors, nutrition deficiency, parasitic infections and their association with the prevalence of anemia. This analysis will help to identify the anemic status of tribal preschool children. Methods: This was a cross-sectional study conducted in 300 children (age: 6 months to 5 years) in Santrampur village, Gujarat. Blood was collected and used to determine complete blood count (CBC); we also performed ELISA (enzyme-linked immunoassay) for the estimation of ferritin, transferrin, sTfR (soluble transferrin receptor), vitamin B12 and vitamin B9 (folate). Stool samples were also collected and assessed by ELISA for Entamoeba histolytica, Giardia lamblia and Cryptosporidium parvum. Microscopy was used to screen samples for malaria. Results: Of the 300 children analyzed, 87.7% were anemic, 239 children were mildly anemic, 20 were moderately anemic and 4 were severely anemic. Mean Hb level was 9.49 1.47 g/dL; males and females had an Hb level of 9.39 1.59 g/dL and 9.58 1.34 g/dL, respectively. Twenty-six children had sickle cell anemia and five had thalassemia. Over 50% of the children had vitamin B12 and B9 deficiency and 16% had abnormalities in CRP (C-reactive protein) levels. Parasitic infection by C. parvum was positively associated the anemia followed by the prevalence of G. lamblia and E. histolytica. Conclusion: An increased awareness of parents in the improvement of sanitary facilities and nutritional counselling with regards to iron-rich food consumption is recommended to if we are to prevent anemia among preschool children. To reduce parasitic infestation, effective periodic deworming measures are also recommended 2022-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7389 Title: Pandemic coerces the use of online resources for dental education Authors: Ullah, Rizwan; Husain, Shehriar; Zafar, Muhammad S. 2022-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7387 Title: In silico analysis of missense variants of the C1qA gene related to infection and autoimmune diseases Authors: Behairy, Mohammed Y.; Abdelrahman, ALi A.; Abdallah, Hoda Y.; Ibrahim, Emad El-Deen A.; Sayed, Anwar A.; Azab, Marwa M. Abstract: Objectives: C1q is a key activator of the classical pathway of the complement system and exerts consequences relating to opsonization and phagocytosis. The C1qA gene is one of three genes encoding the C1q molecule. Defects in C1q, and especially in C1qA, have been linked to an increased susceptibility to infection, sepsis, and systemic lupus erythematosus. These defects could arise from missense single nucleotide polymorphisms (SNPs) and their deleterious impacts on protein structure and function. Thus, identifying highrisk missense SNPs in C1qA has become a necessity if we are to identify appropriate measures for prevention and management of affected patients. Methods: A comprehensive in silico study was conducted to screen the 184 missense SNPs in the C1qA gene using different tools with different algorithms and approaches. We investigated the impact of SNPs on protein function, stability, and structure. In addition, we identified the location of the SNPs on protein domains, secondary structure alignment, and the phylogenetic conservation of their positions. Results: Of the 184 missense SNPs, 10 SNPs were predicted to be the most damaging to protein function and structure. Conclusion: Ten missense SNPs were predicted to have the highest risk of damaging protein function and structure, thus leading to infection, sepsis, and systemic lupus erythematosus. These 10 SNPs constitute the best candidates for further experimental investigations. 2022-01-01T00:00:00Z