http://localhost:8080/xmlui/handle/123456789/6896 477 - 642 2026-04-08T23:14:10Z http://localhost:8080/xmlui/handle/123456789/6954 Title: An unusual and atypical presentation of the novel coronavirus: A case report and brief review of the literature Authors: Alshoabi, Sultan A.; Haider, Kamel H.; Mostafa, Mahmoud A.; Hamid, Abdullgabbar M.; Daqqaq, Tareef S. Abstract: The coronavirus disease 2019 (COVID-19) is a highly contagious novel infection that predominantly presents with fever and respiratory symptoms. However, COVID- 19 can masquerade as an acute coronary syndrome, leg pain or swelling with venous thrombosis, loss of consciousness with cerebral venous thrombosis, confusion, limb weakness with brain infarction, facial neuralgia, acute conjunctivitis, acute appendicitis, and testicular pain. We report on a 42-year-old man who presented with mild symptoms of COVID-19. The patient’s electrocardiogram showed an ST-segment elevation myocardial infarction (STEMI) due to a left coronary thrombosis. The patient was managed conservatively with medicines and had an uneventful recovery. Emergency physicians should have a high index of suspicion for the unusual presentations of COVID-19. 2021-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6953 Title: Non-gestational choriocarcinoma of the ovary: A case report Authors: Yee, Loh S.; Zakaria, Rosnani; Mohamad, Noraini; Fong, Ong W. Abstract: Non-gestational choriocarcinoma of the ovary is an extremely rare clinical condition. Very few cases of this high-grade malignancy of the ovary are reported in the literature worldwide. Given the rarity of the tumour, this disease is generally overlooked, which leads to delayed diagnosis and management. For the attending clinicians, the non-gestational choriocarcinoma of the ovary poses a diagnostic challenge due to its non-specific clinical presentations. A 16-year-old girl presented with pain in the right iliac fossa and with a positive urine pregnancy test. Despite being sexually inactive, the patient was diagnosed with an ectopic pregnancy and underwent emergency laparoscopic surgery. Six weeks later, the histopathological analysis revealed a diagnosis of non-gestational choriocarcinoma of the ovary. Further evaluations showed that her cancer had already advanced to stage IV. In this case report, the non-specific presentations of the disease, radiological features, current treatments, and possible safety strategies are discussed. 2021-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6948 Title: Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl Authors: Albuali, Waleed H.; AlGhamdi, Nora A. Abstract: Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was found to have SARS-CoV-2 without any respiratory symptoms. A 7- year-old girl presented with a history of polydipsia, polyuria, and weight loss. This presentation was complicated by a 2-day history of fatigue and vomiting. Investigations into the patient’s condition confirmed T1DM with DKA. Following the infection control protocol, she underwent screening for SARS-CoV-2, which yielded a positive result. During her hospital stay, she did not develop fever or respiratory symptoms. The ketoacidosis was treated without any complications. We conclude that SARS-CoV-2 may trigger the onset of T1DM and may precipitate the occurrence of DKA in paediatric diabetic patients, even in the absence of respiratory symptoms. 2021-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6944 Title: Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry Authors: Qureshi, Muhammad A.; Syed, Sofia Ali; Sharafat, Shaheen Abstract: Objective: The objective of this report is to provide an overview of lip and oral cavity cancer in Karachi, the largest city in Pakistan. Methods: This study was undertaken at the Dow Cancer Registry. During 2010e2019, all patients who were residents of Karachi who had been diagnosed with lip and oral cavity cancer were registered and recruited for this study. The data were entered in SPSS and MS Excel sheets to investigate frequencies, age-standardized-rates (ASR) and other clinicopathological parameters. The data from our study were compared with the ASR of lip and oral cavity cancer from selected Asian countries. Results: During the defined period, 22,858 cancer cases were registered. Of these, 4,400 (19.2%, ASR 28.0) were lip and oral cavity cancer (the most common type found in males and the second most common type in females), of which 2,986 (67.8%) were found in males, while 1,414 (32.1%) were reported in females. Squamous cell carcinoma was the most common type (97.7%). Most tumours were moderately differentiated (67.7%) followed by poorly (16.6%), and well differentiated (15.7%). Conclusion: We report an alarmingly high ASR of lip and oral cavity cancer in Karachi as compared to Pakistan as a whole and other Asian countries. 2021-01-01T00:00:00Z