http://localhost:8080/xmlui/handle/123456789/6018 199 - 253 2026-04-14T20:40:51Z http://localhost:8080/xmlui/handle/123456789/6041 Title: Breaking the silence: unveiling the intersection of climate change and youth mental health in Indonesia Authors: Kaligis, Fransiska; Wangge, Grace; Fernando, Gabriela; Bagus Nyoman Adi Palguna, Ida; Pramatirta, Billy; Vania Theresia Purba, Natasha Abstract: Breaking the silence: unveiling the intersection of climate change and youth mental health in Indonesia Fransiska Kaligis1 , Grace Wangge2 , Gabriela Fernando2 , Ida Bagus Nyoman Adi Palguna3 , Billy Pramatirta4 , Natasha Vania Theresia Purba4 Brief Communication ABSTRACT In Southeast Asia, home to 362.2 million adolescents, the issue of adolescent mental health is aggravated by climate change. Indonesia, with its large youth population, faces a concerning prevalence of mental health challenges, including anxiety and depression. The intersection of climate change and youth mental health is manifested in the complex interaction of environmental hazards, societal changes, and psychological impact on adolescents and young people. Climate-related hazards exacerbate the existing and give rise to new mental health issues in youths, notably anxiety and post-traumatic stress disorder, and the emerging concepts such as eco-anxiety. Eco-anxiety, a novel concept, amplifies these concerns as youths grapple with climate change-related fears despite not yet being recognized as a formal mental disorder. To address this concern, immediate action should be taken, such as advocating for increased mental health support, youth involvement in climate initiatives, youth advisory committees, increased funding for mental health interventions, and the formulation of a youth centered mental health policy. This call to action is crucial not only for Indonesia but also provides a framework for addressing similar global challenges, empowering adolescents to confront climate-induced mental health issues while nurturing their resilience. KEYWORDS anxiety, climate change, health policy, mental health, youth 2023-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6039 Title: Commonly misdiagnosed round pneumonia in a child: a case report Authors: Quang Tran, Khai; Quang Bui, Nghia; Kieu Anh Pham, Tho Abstract: Commonly misdiagnosed round pneumonia in a child: a case report Khai Quang Tran1 , Nghia Quang Bui1 , Tho Kieu Anh Pham2 , Tri Duc Nguyen3 , Quan Minh Pham1 , Nhu Thi Huynh Tran1 , Ly Cong Tran1 , Nam Hoang Do1 , Phuong Minh Nguyen1 Medical Journal of Indonesia Case Report/Series ABSTRACT Round pneumonia, a specific radiological finding in children, is often caused by Streptococcus pneumoniae; but it is easily misdiagnosed with some other diseases, causing many difficulties for clinicians. We described a case report of round pneumonia in a 9-year-old boy, with chest pain, following fever, productive cough, left-sided pulmonary consolidation syndrome, tachypnea, no chest indrawing, and a round homogenous lesion about 4 cm in diameter with a clear border in the left upper lobe position on chest X-ray. He was initially misdiagnosed as a lung tumor. He was correctly diagnosed with round pneumonia prior to pneumonectomy and was successfully treated with antibiotics. Therefore, it is important to carefully analyze round pneumonia cases that are often misdiagnosed, resulting in poor therapy. KEYWORDS pneumonia, Streptococcus, vancomycin 2023-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6037 Title: Efficacy and safety comparison between silodosin and tamsulosin as medical expulsive therapy for distal ureteral stones Authors: Haidar Fazlur Rahman, Farhan; Leonardo, Kevin; Ardaya, Radhyaksa; Atmoko, Widi; Parikesit, Dyandra Abstract: Efficacy and safety comparison between silodosin and tamsulosin as medical expulsive therapy for distal ureteral stones Farhan Haidar Fazlur Rahman1 , Kevin Leonardo1 , Radhyaksa Ardaya2 , Widi Atmoko1 , Dyandra Parikesit3 Medical Journal of Indonesia Clinical Research ABSTRACT BACKGROUND Ureteral stones are a common urological condition causing significant discomfort and morbidity. Medical expulsive therapy (MET) is a noninvasive approach to facilitate the passage of stones. This study aimed to compare the efficacy and safety of silodosin and tamsulosin as MET in patients with distal ureteral stones (DUS). METHODS We searched CINAHL, Cochrane Library, PubMed, and ScienceDirect for randomized controlled trials (RCTs) on the administration of silodosin and tamsulosin for DUS. The primary outcomes analyzed were stone expulsion rates and expulsion times, measured as risk ratio (RR) and mean difference (MD), respectively. Statistical analyses were performed using Review Manager 5.4 and STATA 17. RESULTS 14 RCTs comprising 1,535 patients (770 received silodosin) met the inclusion criteria. The silodosin group had notably higher stone expulsion rates (RR 1.20, 95% confidence interval [CI] 1.13–1.27, p<0.00001, I² = 37%), shorter expulsion times (MD −2.98, 95% CI −4.35–−1.62, p<0.01, I² = 85%), and fewer colicky pain episodes (MD −0.35, 95% CI −0.59–−0.10, p<0.01, I² = 83%) than the tamsulosin group. Retrograde ejaculation was the only adverse event that had a significant difference between both groups, statistically favoring tamsulosin (RR 1.61, 95% CI 1.12–2.33, p = 0.01, I² = 0%). CONCLUSIONS Silodosin should be preferred as the first-line MET agent for DUS owing to its better expulsion rate, shorter stone expulsion time, and fewer colicky pain episodes. However, tamsulosin may be used in selected cases where patients experience retrograde ejaculation after receiving silodosin. KEYWORDS silodosin, tamsulosin, ureterolithiasis 2023-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/6032 Title: Five-year survival of triple-negative breast cancer and the associated clinicopathological factors: a study in an Indonesian tertiary hospital Authors: Danil Yulian, Erwin; Fachriza, Ihza Abstract: Five-year survival of triple-negative breast cancer and the associated clinicopathological factors: a study in an Indonesian tertiary hospital Erwin Danil Yulian, Ihza Fachriza Medical Journal of Indonesia Clinical Research ABSTRACT BACKGROUND Triple-negative breast cancer (TNBC) has a worse rate of recurrence, survival, and overall survival. This study aimed to find the survival of TNBC and its clinicopathological factors at Cipto Mangunkusumo Hospital. METHODS This study used survival analysis based on clinicopathology in 112 TNBC cases at Cipto Mangunkusumo Hospital, Jakarta, Indonesia, diagnosed from 2009 to 2019. Kaplan–Meier and log-rank tests were used for the analysis. Bivariate and multivariate analyses using Cox regression were performed to obtain the hazard ratios (HRs). RESULTS Most patients were diagnosed at the locally advanced stage (40.2%) compared to the early (33.0%) and metastatic stages (17.9%). The 5-year survival of TNBC was 81.2% with an HR value of 1.372 (p = 0.239) compared to luminal A. Bivariate analyses showed that the older age group with an HR of 6.845 (p = 0.013; CI 1.500–31.243), larger tumor size and extension (T) with an HR of 11.826 (p = 0.001; CI 2.707–51.653), broader regional lymph node involvement (N) with an HR of 8.929 (p = 0.019; CI 1.434–55.587), farther distant metastases (M) with an HR of 3.016 (p = 0.015; CI 1.242–7.322), more lymphovascular invasion with HR of 3.006 (p = 0.018; CI 1.209–7.477), and not operated on cases with an HR of 9.165 (p<0.001; CI 3.303–25.434) significantly shortened the survival of TNBC. Multivariate analysis found that the only factor worsening the survival was not having surgery, with an HR of 6.175 (p<0.001; CI 1.518–34.288). CONCLUSIONS The 5-year survival rate of TNBC patients was 81.2%. Not having surgery was a clinicopathological factor that worsened survival outcomes in TNBC. KEYWORDS breast cancer, Indonesia, prognosis, survival, triple-negative breast cancer 2023-01-01T00:00:00Z