http://localhost:8080/xmlui/handle/123456789/3920 2026-04-11T17:31:06Z http://localhost:8080/xmlui/handle/123456789/4728 Title: Oral care practices of adults in Turkey Authors: Koseoglu, Merve; Bal, Ozge; Bilge Turkan, Hatice; Cetin, Beyza; Nuri Tascioglu, Muhammed Abstract: Oral care practices of adults in Turkey Merve Koseoglu1*, Ozge Bal2, Hatice Bilge Turkan2, Beyza Cetin2, Muhammed Nuri Tascioglu2, Nurullah Aydin2, Ozgur Sancar3, Selma Altindis4 1. Department Prosthetic Dentistry, Faculty of Dentistry, Sakarya University, Sakarya, Turkey 2. Faculty of Dentistry, Sakarya University, Sakarya, Turkey 3. Department of Public Health, Faculty of Medicine, Sakarya University, Sakarya, Turkey 4. Department of Health Administration, Faculty of Management, Sakarya University, Sakarya, Turkey *E-mail: mervekoseoglu89@gmail.com.tr Abstract Background: Information on oral health practices can play a key role in improving a community’s oral health status. The aim of this study was to determine oral healthcare practices of Turkish individuals. Methods: A questionnaire was randomly given to 351 individuals, all of them older than 18 years. This cross-sectional study data were analyzed using descriptive statistical methods and chi-square test. Statistical significance was evaluated at p < 0.05. Results: According this study, 62.1% of individuals visited the dentist only when they needed to. Furthermore, 58% of individuals brushed their teeth twice a day; 12.5% of them used miswak; 50.4% used dental floss, toothpicks, or mouthwash; and 86.6% stated that they didn’t use any other herbal/traditional tooth cleaning method. Additionally, 39.8% of the individuals reported that they ate sweetened foods 1–2 times a day, and 33.6% of them drank acidic beverages 1–2 times a month. Although the frequency of visiting a dentist and using herbal/traditional practices did not differ among individuals (p ˃ 0.05), frequency of consuming sweetened food did differ (p = 0.032). Conclusions: Toothbrushing and interdental cleaning habits differed among individuals, while frequency of dentist visits and alternative methods of cleaning teeth did not differ. Keywords: adult, dental plaque, oral hygiene, periodontal disease 2020-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4727 Title: A high glucose concentration is well tolerated by colorectal adenocarcinoma and melanoma cells but toxic to normal human gingival fibroblast: Results of an in vitro investigation Authors: Alif Mazlan, Muhammad; Mat Yusof, Afzan; Lokman Md Isa, Muhammad Abstract: A high glucose concentration is well tolerated by colorectal adenocarcinoma and melanoma cells but toxic to normal human gingival fibroblast: Results of an in vitro investigation Muhammad Alif Mazlan1,2, Afzan Mat Yusof1,2, Muhammad Lokman Md. Isa1,2* 1. Department Basic Medical Sciences for Nursing, International Islamic University Malaysia, Kuantan 25200, Malaysia 2. Human Molecular and Cellular Biology Research Cluster (iMoleC), International Islamic University Malaysia, Kuantan 25200, Malaysia *E-mail: lokman@iium.edu.my Abstract Background: Glucose is associated with weight gain, which increases the risk of cancer. There is insufficient information on the effects of high glucose concentrations on cell lines. This study evaluated the viability patterns of human cancer and normal cell lines treated with glucose. Methods: Human gingival fibroblast (hGF), colorectal adenocarcinoma (HT29), and skin malignant melanoma (A375) cell lines were cultured and treated with additional glucose in three respective concentrations: 1 mg/ml, 5 mg/ml, and 10 mg/ml. Then, cell viability was measured using an MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide)-assay. The data were analyzed using the Statistical Package for the Social Sciences software. Results: The hGF cells’ percentage pattern of viability showed a rapid decline of nearly 95% on the third day of treatment. Both HT29 and A375 were able to survive in the high glucose condition when the cell viability percentage was above 100% on Day 5. The data exhibited significance; the p-value was less than 0.001. Conclusion: The high glucose concentration can be toxic to hGF. In addition, HT29 and A375 might be adaptive to the hyperglycaemic condition. Keywords: in vitro technique, fibroblasts, adenocarcinoma, malignant melanoma, glucose, cancer 2020-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4726 Title: Cervical cancer vaccination awareness and acceptance among the females of Punjab, Pakistan Authors: Minhas, Sadia; Sajjad, Aneequa; Kashif, Muhammad; Rehman, Zobaria; Idrees, Muhammad Abstract: Cervical cancer vaccination awareness and acceptance among the females of Punjab, Pakistan Sadia Minhas1*, Aneequa Sajjad1, Muhammad Kashif 2, Zobaria Rehman3, Muhammad Idrees4, Farheen Ansari5 1. Department of Oral Pathology, Akhtar Saeed Dental College, University of Lahore, Lahore 54590, Pakistan 2. Department of Oral Pathology, Bakhtawar Amin Medical & Dental College, Multan 60000, Pakistan 3. Center of Applied Molecular Biology, University of Punjab, Lahore 54590, Pakistan 4. Genome Center, CL-25, Block-B Abdalian Corporative Housing Society, Shaukat Kahnnum road, Lahore 54770, Pakistan 5. Institute of Molecular Biology and Biotechnology, Microbiology Department, University of Lahore, Lahore 54590, Pakistan *E-mail: sadiawasif81@gmail.com Abstract Background: In developing countries like Pakistan, it is essential for health care professionals to have comprehensive knowledge regarding cervical cancer. Methods: A cross-sectional self-administered paper-based questionnaire was administered to patients from 2016 to 2018. This study included 200 females who attended the gynecological OPD of Lady Willingdon Hospital Lahore, Punjab. We evaluated cervical cancer knowledge, screening, prevention, and acceptance towards the vaccination. Data entry and analysis were performed using SPSS version 20. Results: The perception and knowledge related to cervical cancer (28%), screening (3%), prevention (3%), and vaccination (1%) among the females were poor, but a positive attitude was observed towards cervical cancer screening, vaccination, and awareness programs. An extreme lack of knowledge was observed regarding the risk factors associated with cervical cancer and the availability of the cervical cancer vaccine (99%). A significant association (p > 0.005) was noted among the level of education and awareness of cervical cancer, its mode of transmission, and screening tests. Conclusion: The knowledge and perception of cervical cancer and its vaccine among the females of Punjab, Pakistan were inadequate. Efforts should be made to prevent and control cervical cancer in Pakistan by establishing proper strategies, such as health education programs through health care providers and media support. Keywords: cervical cancer, HPV, pap smear, screening, vaccination 2020-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4725 Title: Trace elements in maternal serum and their relationships with preterm birth and fetal growth restriction Authors: Irwinda, Rima; Sungkar, Ali; Surya, Raymond; Tiempo Guinto, Valerie Abstract: Trace elements in maternal serum and their relationships with preterm birth and fetal growth restriction Rima Irwinda1, Ali Sungkar1, Raymond Surya1*, Valerie Tiempo Guinto2 1. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Depok 16424, Indonesia 2. Maternal-Fetal Medicine Phillipine General Hospital, University of the Philippines, Los Baños 4031, Philippines *E-mail: raymond_s130291@yahoo.co.id Abstract Background: Preterm birth (PTB) and fetal growth restriction (FGR) contribute to high hospital costs. An imbalance in the concentration of the four trace elements (i.e., copper, zinc, iron, and calcium) was shown to be associated with complications during pregnancy. This study aimed to analyze the role of these trace elements in the occurrence of PTB and FGR. Methods: A search was conducted in PubMed, Cochrane Library, and Ovid. The articles were filtered based on the inclusion and exclusion criteria, and further screening was based on the association of articles with the clinical question. The risk of bias in each of the studies was assessed using the Cochrane risk of bias table. Forrest plots were created and analyzed using Review Manager 5.3e. Results: Three studies were included in the risk of bias assessment and meta-analysis. Maternal serum levels of copper and iron were lower in the FGR group (p < 0.05), while copper, zinc, iron, and calcium were lower in the PTB group (p < 0.05). The included studies had a low degree of homogeneity (I2 < 50%). Conclusion: Maternal iron deficiency was associated with FGR, while low levels of the trace elements copper, zinc, iron, and calcium were associated with PTB. Keywords: fetal growth restriction, premature birth, trace elements 2020-01-01T00:00:00Z