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Clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia: a cross-sectional study

2024-10-28T06:56:31Z

Title: Clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia: a cross-sectional study Authors: S Alyami, Hamad; Y Naser, Abdallah; H. Alyami, Mohammad; Banihameem, Ibraheem S.; Almusabi, Mohammad; Alqahtani, Ahlam M.; A. Gannas, Mohammed DKK. Abstract: ABSTRACTThere are limited studies in the Southern region of Saudi Arabia on the characteristics of hospitalised patients with cancer.The aim of this study was to explore the clinical and therapeutic characteristics of hospitalized cancer patients in the Najran Region of Saudi Arabia. A retrospective cross-sectional observational study was conducted using cancer patients’ medical records at the oncology unit in the King Khalid Hospital in Najran situated in the southern region of Saudi Arabia. Hospitalized patients’ records were extracted between 2014 and 2020. Logistic regression analysis was conducted to identify determinants of ICU admission among cancer patients.A total of 1,678 patients were involved in this study. The mean age was 52.5 (SD: 21.1) years. The average duration of stay was 8.7 days (SD: 13.4). The most commonly reported types of cancer were breast cancer, rectum cancer and colon cancer, accounting for 13.6%, 6.9%, and 6.7%, respectively. A total of 13.9% of the study participants required ICU admission. More than half (57.1%) of the patients were complaining of a moderate to severe case upon hospitalization.Older age (52.5 years and above) and the presence of comorbidities were risk factors that significantly increased the risk of ICU admission (P<.001). Patients with diabetes mellitus, hypertension, heart diseases, stroke, and kidney diseases were more likely to require ICU admissions. Patients with liver cancer were more likely to require ICU admission. Healthcare professionals should give extra care and health education for high risk cancer patients including elderly patients and those with other comorbidities to prevent complications and its associated hospitalization. Keywords: Admission; Cancer; Hospitalized; Najran.

Knowledge of Cardiovascular Disease and its Association Among General Population in Indonesia

2024-10-28T06:40:55Z

Title: Knowledge of Cardiovascular Disease and its Association Among General Population in Indonesia Authors: Anggelina, Bella; Ari Kristina, Susi; Wiedyaningsih, Chairun Abstract: ABSTRACTKnowledge of cardiovascular disease is essential for providing information about healthy behavior and to be proactive in reducing modifiable risk factors, control prevention, and improving early recognition. The existing study about knowledge of CVD in Indonesia is still limited. Hence, this study aimed to describe knowledge of CVD among general population in Indonesia and its association.A cross-sectional survey was conducted in 34 provinces in Indonesia from November-December 2021. Data were retrieved using a self-administered questionnaire. The Chi-Square analysis was performed to determine the association that contributes to overall knowledge of CVD.Among the 694 participants, 32.1% originated from Java, with the median age was 24 years and dominated by women (72.5%). The mean score of overall CVD knowledge was 59.6%, and only 39.1% of the participants had good knowledge of CVD. Cerebrovascular disease (94.7%) was the most identified various type of CVD. Likewise, unhealthy diet (77.2%), obesity (74.6%), and lack ofexercise (72.5%) were the most identified risk factors. More than 50% of the participants recognized heart attack symptoms such as chest pain (77.1%) and shortness of breath (66.1%). Meanwhile, numbness or weakness (84.7%), trouble speaking (76.9%), and loss of balance (72.3%) were recognized as stroke symptoms. Gender, age, education level, working status, healthy food, smoking status, family history of CVD, ever checked blood pressure, fasting blood glucose, and total cholesterol were associated with overall knowledge of CVD. The disparity between level of CVD knowledge is not prominent among general population in Indonesia and further study need to establish.Keyword:Cardiovascular disease; Heart attack; Knowledge; Risk factors; Stroke.

Perbandingan Angka Kematian Terapi Antiviral Favipiravir dan Remdesivir pada Pasien COVID-19 Di RSUP Dr. Sardjito Yogyakarta

2024-10-28T05:04:38Z

Title: Perbandingan Angka Kematian Terapi Antiviral Favipiravir dan Remdesivir pada Pasien COVID-19 Di RSUP Dr. Sardjito Yogyakarta Authors: Satriyani, Nova; Rahmawati, Fita; Murti Andayani, Tri Abstract: ABSTRAKTatalaksana antivirus pada SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2) hingga saat ini masih diteliti efektivitasnya. Antivirus pada pedoman tatalaksana COVID-19 edisi 3 bulan Juli 2021 yaitu favipiravir dan remdesivir digunakan untuk derajat sedang, berat, dan kritis. Penelitian bertujuan membandingkan angka kematian pasien COVID-19yangmenggunakanantiviral favipiravir dan remdesivir. Penelitian ini merupakan penelitian cohort retrospectiveyang dilakukan di RSUP Dr. Sardjito Yogyakarta. Data penelitian dari rekam medik pasien yang terdiagnosis COVID-19 derajat sedang, berat, dan kritis yang dirawat selama periode Januari-Desember 2021. Sejumlah 99 pasien (50,8%) menggunakan favipiravir, sedangkan remdesivir sebanyak 97 pasien (49,5%). Analisis Chi-squaredan multiple logistic regression digunakan untuk mengetahui hubungan variabel penelitian. Subjek penelitian dengan persentase terbanyak usia 46-65 tahun (65%), jenis kelamin laki-laki (54,6%), komorbid diabetes melitus dan hipertensi (13,3%), derajat keparahan berat (60,7%), dan viral loadnilai CT ≤ 29 (80,1%), pasien pulang hidup (61,2%), dan meninggal (38,8%).Jenis antiviral tidak berpengaruh terhadap angka kematian (p > 0,05). Penelitian lebih lanjut diperlukan dengan karakteristik kedua kelompok yang sama melibatkan faktor derajat keparahan, jenis komorbid dan jenis terapi.Kata Kunci:COVID-19; Favipiravir; Kematian; Remdesivir

Evaluasi Sistem Informasi Manajemen pada Laporan Pemakaian dan Lembar Permintaan Obat di Puskesmas X

2024-10-28T04:57:23Z

Title: Evaluasi Sistem Informasi Manajemen pada Laporan Pemakaian dan Lembar Permintaan Obat di Puskesmas X Authors: Putri Pratitis, Mera; Merari Peranginangin, Jason; Purwidyaningrum, Ika Abstract: ABSTRAKElemen persyaratan dalam pengadaan obat yaitu Laporan Pemakaian dan Lembar Permintaan Obat (LPLPO). Penerapan Sistem Informasi Manajemen (SIM) di Puskesmas X belum memenuhi fungsi penyusunan LPLPO, sehingga hal tersebut berdampak pada perencanaan dan pengadaan obat. Penelitian ini bertujuan untuk mengevaluasidan mengetahui rancangan pengembangan SIM pada LPLPO di Puskesmas X Kota Surakarta. Penelitian ini merupakan penelitian deskriptif kualitatif dengan analisis induktif. Pengambilan sampel dalam penelitian ini dilakukan secara purposive sampling. Sampel dalam penelitian ini yaitu petugas yang mengoperasikan SIM baik Apoteker maupun Tenaga Teknis Kefarmasian (TTK) minimal selama 1 tahun. Penelitian ini dilaksanakan di Puskesmas X Kota Surakarta pada bulan September-Oktober2021. Perancangan sistem dalam penelitian ini menggunakan metode prototypeberdasarkan hasilwawancara. Wawancara dilakukan sebagai evaluasi SIM menggunakan metode PIECES Frameworkdengan melibatkan 4 informan. Desain perancangan SIM dibuat dengan menggunakan Diagram Konteks dan Data Flow Diagram(DFD). Hasil evaluasi dengan PIECES Frameworkmenunjukkan bahwa SIM yang diterapkan dapat memberikan kemudahan pengguna dalam mengelola persediaan obat meskipun belum dioptimalkan dan belum memenuhi kebutuhan, sehingga SIM tersebut layak untuk dikembangkan. Berdasarkan hasil evaluasi dapat disimpulkan bahwa penerapan SIM dapat membantu dan memudahkan tenaga farmasi dalam melaksanakan pekerjaan dengan memberikan data dan informasi yang akurat dan lengkap sebagai data dukung untuk penyusunan LPLPO, tetapi belum bisa digunakan untuk memantau ED obat dan menyusun LPLPO otomatis. Kata Kunci:Desain SIM; LPLPO;PIECES Framework.